SML1573

Tolrestat

≥98% (HPLC)

• Sinónimos: AY-27773, CID 53359, N-[[5 -(Trifluoromethyl)-6-methoxy-lnaphthalenyl]thioxomethyl]-N-methylglycine, Tolrestatin, N-[[6-Methoxy-5-(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methyl-glycine
• Empirical Formula (Hill Notation): C₁₆H₁₄F₃NO₃S
• Número de CAS: 82964-04-3
• Peso molecular: 357.35
• NACRES: NA.77

Propiedades

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• InChI: 1S/C16H14F3NO3S/c1-20(8-13(21)22)15(24)11-5-3-4-10-9(11)6-7-12(23-2)14(10)16(17,18)19/h3-7H,8H2,1-2H3,(H,21,22)
• InChI key: LUBHDINQXIHVLS-UHFFFAOYSA-N

Descripción

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Tolrestat is considered to be effective in treating the consequences of diabetes including neuropathy, nephropathy, retinopathy and esophageal motility and vibration perception. Tolrestat is also believed to have lesser or no toxic effects.

Tolrestat is an orally active and potent aldose reductase inhibitor. Studies have also shown that it reduces RBC (red blood cells) sorbitol levels in rats.

Información de seguridad

• RIDADR: NONH for all modes of transport
• WGK Germany: WGK 3