Merck
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SML1573

Sigma-Aldrich

Tolrestat

≥98% (HPLC)

Synonym(s):
AY-27773, CID 53359, N-[[5 -(Trifluoromethyl)-6-methoxy-lnaphthalenyl]thioxomethyl]-N-methylglycine, Tolrestatin, N-[[6-Methoxy-5-(trifluoromethyl)-1-naphthalenyl]thioxomethyl]-N-methyl-glycine
Empirical Formula (Hill Notation):
C16H14F3NO3S
CAS Number:
Molecular Weight:
357.35
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

white to beige

solubilidad

DMSO: 20 mg/mL, clear

temp. de almacenamiento

2-8°C

InChI

1S/C16H14F3NO3S/c1-20(8-13(21)22)15(24)11-5-3-4-10-9(11)6-7-12(23-2)14(10)16(17,18)19/h3-7H,8H2,1-2H3,(H,21,22)

InChI key

LUBHDINQXIHVLS-UHFFFAOYSA-N

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

Tolrestat is considered to be effective in treating the consequences of diabetes including neuropathy, nephropathy, retinopathy and esophageal motility and vibration perception. Tolrestat is also believed to have lesser or no toxic effects.
Tolrestat is an orally active and potent aldose reductase inhibitor. Studies have also shown that it reduces RBC (red blood cells) sorbitol levels in rats.

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Certificate of Analysis

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Certificate of Origin

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