SML1828

EMD-87580

≥98% (HPLC)

• Synonym(s): EMD87580, N-[2-methyl-4,5-bis(methylsulfonyl)-benzoyl]-guanidine
• Empirical Formula (Hill Notation): C₁₁H₁₅N₃O₅S₂
• CAS Number: 187870-78-6
• Molecular Weight: 333.38

Properties

• Nivel de calidad: 100
• ensayo: ≥98% (HPLC)
• formulario: powder
• color: white to beige
• solubilidad: DMSO: 20 mg/mL, clear
• temp. de almacenamiento: −20°C
• SMILES string: NC(NC(C1=CC(S(=O)(C)=O)=C(S(=O)(C)=O)C=C1C)=O)=N

Description

Aplicación

EMD-87580 has been used as a selective and potent sodium-hydrogen antiporter 1 (NHE-1) inhibitor in cardiac ventricular myocytes to test its effect on the hypertrophic response.

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

EMD-87580 is a selective inhibitor of the Na+/H+ exchanger subtype 1 (NHE-1), also known as the Na+/H+ antiporter. EMD-87580 has shown cardioprotective effects, and has been investigated as a possible treatment for Duchenne′s muscular dystrophy.

Safety Information

• Código de clase de almacenamiento: 11 - Combustible Solids
• WGK: WGK 3
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable