Merck
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SML1874

Sigma-Aldrich

DM-NOFD

≥98% (HPLC)

Synonym(s):
Dimethyl N-oxalyl-D-phenylalanine, N-(2-Methoxy-2-oxoacetyl)-D-phenylalanine methyl ester, N-Oxalyl-D-phenylalanine dimethyl ester
Empirical Formula (Hill Notation):
C13H15NO5
CAS Number:
Molecular Weight:
265.26
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

oil

color

, colorless to dark yellow

temp. de almacenamiento

2-8°C

SMILES string

O=C(C(N[C@H](CC1=CC=CC=C1)C(OC)=O)=O)OC

Descripción general

Dimethyl N-oxalyl-D-phenylalanine (DM-NOFD) is a small FIH (factor-inhibiting) inhibitor molecule.

Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

DM-NOFD is a cell penetrant, prodrug of NOFD a potent and selective inhibitor of an asparaginyl hydroxylase FIH (factor-inhibiting HIF). DM-NOFD efficiently reduces HIF1a CAD (C-terminal activating domain) hydroxylation in MCF-7 cells.

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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