SML2107

Sigma-Aldrich

Tulathromycin A

≥95% (HPLC)

Sinónimos:
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-2,6-dideoxy-3-C-methyl-3-O-methyl-4-C-(propylamino)methyl-a-L-ribo-hexopyranosyloxy-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-3,4,6-trideoxy-3-(dimethylamino)-b-D-xylo-hexopyranosyloxy-1-oxa-6-azacyclopentadecan-15-one, CP-472295
Empirical Formula (Hill Notation):
C41H79N3O12
Número de CAS:
Peso molecular:
806.08
MDL number:
NACRES:
NA.77
En este momento no podemos mostrarle ni los precios ni la disponibilidad

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

CC@@(C@H(OC(C@@H(C@H1OC@2(H)OC@@H(C)C@@(O)(CNCCC)C@@(C2)(OC)C)C)=O)CC)(C@@H(C@H(NCC@H(C)CC@(C@@H(C@H1C)OC@3(H)OC@H(C)CC@H(N(C)C)C@H3O)(O)C)C)O)O

Biochem/physiol Actions

Tulathromycin is a triamilide antimicrobial, which is structurally similar to the di-basic azalide antibiotic azithromycin. It is used to treat bovine and swine bacterial respiratory diseases.
Tulathromycin A is a macrolide antibiotic. It binds to the subunit 50S of the bacterial ribosome, interfering with bacterial protein synthesis.

pictograms

Exclamation mark

signalword

Warning

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

Haihong Hao et al.
Frontiers in microbiology, 7, 477-477 (2016-04-20)
To evaluate microbiological safety of tulathromycin on human intestinal bacteria, tulathromycin (0, 0.1, 1, 10, and 100 μg/mL) was added into Chemostats. Before and after drug exposure, we monitored (1) population, SCFA products, antimicrobial resistance, and colonization resistance of gut...
Nicolas Villarino et al.
Veterinary journal (London, England : 1997), 198(2), 352-357 (2013-11-26)
Tulathromycin is the first and only member of the triamilide sub-class of macrolides that is used therapeutically and has been registered in more than 30 countries across America, Europe, Oceania and Asia. The discovery of tulathromycin and its registration in...
Qiaoyi Zhou et al.
Frontiers in pharmacology, 8, 392-392 (2017-07-14)
Tulathromycin, a macrolide antibiotic, is used for the treatment of respiratory disease in cattle and swine. The aim of our study was to investigate the
An analytical method for the analysis of tulathromycin, an equilibrating triamilide, in bovine and porcine plasma and lung
Galer D, et al.
Journal of Agricultural and Food Chemistry, 52(8), 2179-2191 (2004)
Analytical procedure for the determination of tulathromycin in swine plasma
Gajda A, et al.
Bulletin of the Veterinary Institute in Pulawy, 57(2), 191-195 (2013)

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