Merck
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SML2184

Sigma-Aldrich

Kevetrin hydrochloride

≥98% (HPLC)

Synonym(s):
Kevetrin hydrochloride, 4-Isothioureidobutyronitrile hydrochloride, Carbamimidothioic acid 3-cyanopropyl ester hydrochloride, NSC 525990 HCl
Empirical Formula (Hill Notation):
C5H9N3S · HCl
CAS Number:
Molecular Weight:
179.67
Número MDL:
NACRES:
NA.77

ensayo

≥98% (HPLC)

formulario

powder

condiciones de almacenamiento

desiccated

color

white to beige

solubilidad

H2O: 2 mg/mL, clear

temp. de almacenamiento

−20°C

SMILES string

NC(SCCCC#N)=N.Cl

Acciones bioquímicas o fisiológicas

Kevetrin is an activator/stabilizer of wild type p53 tumor suppressor protein in human lung carcinoma and ovarian cancer cells that induces cell cycle arrest and apoptosis. Additionally Kevetrin down-regulates oncogenic mutant p53 in OVCAR-3 ovarian cancer cells. Kevetrin inhibits tumor growth in xenograft model of ovarian cancer.

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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