Merck
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SML2193

Sigma-Aldrich

Altenusin

≥98% (HPLC)

Synonym(s):
3,4′,5′-Trihydroxy-5-methoxy-2′-methyl[1,1′-biphenyl]-2-carboxylic acid, Alutenusin
Empirical Formula (Hill Notation):
C15H14O6
CAS Number:
Molecular Weight:
290.27
NACRES:
NA.77

origen biológico

Penicillium sp.

ensayo

≥98% (HPLC)

formulario

powder

color

yellow to orange

temp. de almacenamiento

−20°C

SMILES string

OC1=CC(C2=CC(OC)=CC(O)=C2C(O)=O)=C(C)C=C1O

InChI

1S/C15H14O6/c1-8-5-13(16)14(17)7-11(8)12-6-9(20-2)3-4-10(12)15(18)21-19/h3-7,16-17,19H,1-2H3

InChI key

GWGIZSANXIQQQR-UHFFFAOYSA-N

Acciones bioquímicas o fisiológicas

Altenusin, a non-steroidal fungal metabolite, is a potent and selective agonist of Farnesoid X receptor (FXR) that protects mice from high-fat diet induced obesity. Also it decreases blood glucose level, serum insulin level, and reduces lipid droplets accumulation. Altenusin inhibits trypanothione reductase from Trypanosoma cruzi.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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