Merck
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SML2492

Sigma-Aldrich

Engeletin

≥98% (HPLC)

Synonym(s):
(+)-(2R,3R)-Dihydrokaempferol 3-O-α-L-rhamnoside, (2R,3R)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, (2R,3R)-Engelitin, Dihydrokaempferol 3-O-α-L-rhamnopyranoside, Dihydrokaempferol 3-rhamnoside, Engelitin
Empirical Formula (Hill Notation):
C21H22O10
CAS Number:
Molecular Weight:
434.39
Número MDL:

ensayo

≥98% (HPLC)

formulario

powder

actividad óptica

[α]/D -13 to -17°, c = 0.5 in pyridine

color

white to beige

solubilidad

DMSO: 2 mg/mL, clear

temp. de almacenamiento

−20°C

InChI

1S/C21H22O10/c1-8-15(25)17(27)18(28)21(29-8)31-20-16(26)14-12(24)6-11(23)7-13(14)30-19(20)9-2-4-10(22)5-3-9/h2-8,15,17-25,27-28H,1H3/t8-,15-,17+,18+,19+,20-,21-/m0/s1

InChI key

VQUPQWGKORWZII-WDPYGAQVSA-N

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This Item
PHL83279PHL80449Y0001611
Engeletin ≥98% (HPLC)

Sigma-Aldrich

SML2492

Engeletin

Engeletin phyproof® Reference Substance

PHL83279

Engeletin

Esculetin phyproof® Reference Substance

PHL80449

Esculetin

Esculetin European Pharmacopoeia (EP) Reference Standard

Y0001611

Esculetin

assay

≥98% (HPLC)

assay

≥98.0% (HPLC)

assay

≥95.0% (HPLC)

assay

-

form

powder

form

-

form

powder

form

-

color

white to beige

color

-

color

-

color

-

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

-

solubility

-

storage temp.

−20°C

storage temp.

-

storage temp.

-

storage temp.

2-8°C

optical activity

[α]/D -13 to -17°, c = 0.5 in pyridine

optical activity

-

optical activity

-

optical activity

-

Acciones bioquímicas o fisiológicas

New MCE product August 2018. Engeletin is a flavanonol glycoside present in the skin of white grapes and white wine that exhibits anti-inflammatory activities. It inhibits LPS induced cytokines production in mouse J774A.1 macrophages. Also, engeletin attenuates LPS-induced endometritis in mice through inhibiting NF-κB activation, and inhibits inflammatory response in LPS-induced acute lung injury (ALI).

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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