Merck
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SML2617

Sigma-Aldrich

Celiprolol hydrochloride

≥98% (HPLC)

Synonym(s):
Selecor, Celiprolol hydrochloride, NSC 324509, (3-[3-Acetyl-4-(3-t-butylamino-2-hydroxypropoxy)phenyl]-2,1-diethylurea hydrochloride, REV 5320A, ST 1396, Tenoloc
Empirical Formula (Hill Notation):
C20H33N3O4 · HCl
CAS Number:
Molecular Weight:
415.95
Número MDL:

ensayo

≥98% (HPLC)

formulario

powder

color

white to beige

solubilidad

H2O: 2 mg/mL, clear

temp. de almacenamiento

2-8°C

InChI

1S/C20H33N3O4.ClH/c1-7-23(8-2)19(26)22-15-9-10-18(17(11-15)14(3)24)27-13-16(25)12-21-20(4,5)6;/h9-11,16,21,25H,7-8,12-13H2,1-6H3,(H,22,26);1H

InChI key

VKJHTUVLJYWAEY-UHFFFAOYSA-N

Acciones bioquímicas o fisiológicas

Celiprolol is a selective adrenoceptor modulator that acts not only as a selective β1 receptor antagonist, but also as a β2 receptor partial agonist. Because of its of its β2 agonist activity, celiprolol lacks the typical side effects of the beta-blockers, such as bronchoconstriction, depression of left ventricular function, and peripheral vasoconstriction, making it a good candidate for patients with both cardiovascular and pulmonary disease. It is currently being investigated for treatment of vascular Ehlers-Danlos Syndrome (vEDS).

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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