Merck
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SML2918

Sigma-Aldrich

INT131

≥98% (HPLC)

Synonym(s):
AMG-131, T0903131, 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide
Empirical Formula (Hill Notation):
C21H12Cl4N2O3S
CAS Number:
Molecular Weight:
514.21
Número MDL:

Nivel de calidad

100

ensayo

≥98% (HPLC)

formulario

powder

color

white to beige

solubilidad

DMSO: 2 mg/mL, clear

temp. de almacenamiento

2-8°C

Acciones bioquímicas o fisiológicas

INT131 is a brain penetrant, non-thiazolidinedione, highly potent and selective peroxisome proliferator-activated receptor gamma (PPARγ) modulator (SPPARM) that displays anti-diabetic activities. INT131 is a partial, rather than a full agonist of PPARγ, and in clinical trials has shown increased glucose tolerance without the weight gain and cardiovascular side effects seen with some of the full agonist.

Código de clase de almacenamiento

11 - Combustible Solids

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