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SRP0715

Sigma-Aldrich

PEAK1, UNACTIVE

recombinant

recombinante

expressed in baculovirus infected Sf9 cells

ensayo

70-95% (SDS-PAGE)

formulario

frozen liquid

mol peso

~100 kDa

concentración

0.1 μg/μL

nº de acceso

NM_024776

enviado en

dry ice

temp. de almacenamiento

−70°C

Gene Information

human ... PEAK1(79834)

Aplicación

Useful for kinase assay and Western blot.

Acciones bioquímicas o fisiológicas

Recombinant human PEAK1 (1127-end) was expressed by Baculovirus in Sf9 insect cells using an N-terminal GST tag. PEAK1 or Pseudopodium-enriched atypical kinase 1 is a protein tyrosine kinase which belongs to NKF3 kinase family and regulates the cytoskeleton and has been shown to be involved in cancer progression (1). PEAK1 promotes anchorage-independent growth in the MDA-MB-435 human cancer cell line and promotes tumor progression of XPA-1 human pancreatic cancer cells when transplanted into the pancreas of nude mice. PEAK1 is highly expressed in spleen, followed by heart, ovary, brain, lung, kidney, and fetal brain (2).

Reconstitución

Formulated in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

Almacenamiento y estabilidad

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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