SRP2028

TFIIA, reconstituted human

recombinant, expressed in E. coli, ≥80% (SDS-PAGE)

• Sinónimos: TF2A1, TFIIA, TF2A2, MGC129969
• NACRES: NA.26

Propiedades

• biological source: human
• recombinant: expressed in E. coli
• assay: ≥80% (SDS-PAGE)
• form: frozen liquid
• mol wt: 66 kDa
• packaging: pkg of 10 μg
• storage condition: avoid repeated freeze/thaw cycles
• concentration: 150 μg/mL
• color: clear colorless
• NCBI accession no.: NM_004492; NM_015859
• UniProt accession no.: P52655
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... GTF2A1(2957), GTF2A2(2958)

Descripción

Biochem/physiol Actions

The transcription factor IIA (TFIIA) has been shown to bind to the TBP-DNA complex and to increase the affinity of TBP for the TATA element. Human TFIIA consists of three subunits of 35 kDa (α subunit), 19 kDa (β subunit) and 12 kDa (γ subunit). The α and β subunits are derived from the product, p55, of a single gene by an unknown mechanism. However, recombinant p55, in combination with a 12 kDa subunit (γ subunit), retains native TFIIA activity.

Physical form

Clear and colorless frozen liquid solution

Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Información de seguridad

• RIDADR: NONH for all modes of transport
• WGK Germany: WGK 1
• Flash Point F: Not applicable
• Flash Point C: Not applicable