Merck
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SRP4304

Sigma-Aldrich

NGF-beta from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

Synonym(s):
Nerve Growth Factor β, Ngf, Ngfb
NACRES:
NA.32

origen biológico

mouse

recombinante

expressed in E. coli

ensayo

≥98% (SDS-PAGE)

formulario

lyophilized

potencia

0.2 ng/mL ED50

mol peso

~13.4 kDa

envase

pkg of 20 μg

impurezas

endotoxin, tested

Nº de acceso NCBI

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

mouse ... Ngf(18049)

Descripción general

Nerve growth factor-β (NGF-β) belongs to the neurotrophin family. The active form of human NGF-β is a homodimer, non-glycosylated chain.

Acciones bioquímicas o fisiológicas

Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. It brings pro-survival effects with the help of receptor tyrosine kinase TrkA. NGF-β is associated with diabetic neuropathy and ischemic heart disease. It is also involved in airway nerve system. NGF-β is also responsible for the pain which is linked with osteoarthritis (OA). It is involved in liver fibrosis, carcinogenesis, angiogenesis and cholangiocyte proliferation.

Forma física

Lyophilized without any additives.

Reconstitución

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in water to a concentration of 0.1-1.0 mg/mL containing 1% HSA or BSA. The solution can be diluted into other aqueous buffers and stored at 4°C for 2-7 days or store at –20°C for future use.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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