Merck
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SRP4515

Sigma-Aldrich

Artemin human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

Synonym(s):
ART, ARTN, EVN, NBN
Número MDL:

origen biológico

human

recombinante

expressed in E. coli

ensayo

≥98% (SDS-PAGE)

formulario

lyophilized

potencia

2-5 ng/mL ED50 (it′s ability to stimulate the proliferation of human SH-SY5Y cells)

mol peso

~24 kDa

envase

pkg of 20 μg

condiciones de almacenamiento

avoid repeated freeze/thaw cycles

impurezas

endotoxin, tested

Nº de acceso NCBI

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

human ... ARTN(9048)

Descripción general

Human Artemin, a neurotrophic factor, belongs to the GDNF family. Artemin is a survival factor for sensory and sympathetic neurons in culture. Recombinant human Artemin is a 24.2 kDa, disulfide-linked homodimer formed by two identical 113 amino acid subunits. The gene encoding this protein is localized on human chromosome 1p34.1.

Acciones bioquímicas o fisiológicas

Artemin (ART/ARTN) is a survival factor for sensory and sympathetic neurons in culture. It has a role in promoting survival of neurons. ART is also involved in the differentiation and development of the central and peripheral nervous systems. The protein promotes axonal projection and migration in sympathetic neurons. Artemin restores neural damage and diminishes neuropathic pain. It has been associated with various carcinomas.

Forma física

Lyophilized from 10 mM Sodium Citrate pH 4.5 plus 150 mM NaCl.

Nota de preparación

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitución

Reconstitute in water to a concentration of 0.1-0.5 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
Recontitute in PBS containing at least 0.1% BSA to a concentration of 0.1-1.0 mg/mL. This stock solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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