Merck
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SRP4524

Sigma-Aldrich

BD-3 human

recombinant, expressed in E. coli

Synonym(s):
HBP3, HBD3, DEFB3, HDB-3, DEFB103
NACRES:
NA.32

origen biológico

human

recombinante

expressed in E. coli

formulario

lyophilized

mol peso

~5 kDa

envase

pkg of 20 μg

condiciones de almacenamiento

avoid repeated freeze/thaw cycles

impurezas

endotoxin, tested

Nº de acceso NCBI

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

Descripción general

β-defensin-3 (BD-3) is an anti-microbial peptide produced by airway epithelial cells, lung-derived epithelial cells and keratinocytes. It has a molecular weight of 5kDa. The gene encoding this protein is localized on human chromosome 8p23.1. Recombinant human β-defensin-3 (BD-3) is an antimicrobial peptide, which belongs to the distinct family of β-defenisns. Recombinant human BD-3 is a 5.1 kDa protein containing 45 amino acid residues.
Chemical structure: peptide

Acciones bioquímicas o fisiológicas

β-defensin-3 (BD-3) associates with bacterial products which reduce the effect of inflammatory cytokine responses. The protein has been shown to stimulate the production of interferon-α and activate monocytes through toll-like receptors 1 and 2. It antagonizes the activation of C-X-C motif chemokine receptor 4 (CXCR4).

Forma física

Sterile filtered and lyophilized with no additives.

Reconstitución

Reconstitute in 10 mM Acetic acid to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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