- SRP5163
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SRP5163
ATF1, GST tagged human
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
All Photos(1)
Synonym(s):
EWS-ATF1, FUS/ATF-1, TREB36
NACRES:
NA.32
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This Item | SRP5341 | SRP2136 | SRP2148 |
|---|---|---|---|
| recombinant expressed in baculovirus infected Sf9 cells | recombinant expressed in E. coli | recombinant expressed in E. coli | recombinant expressed in E. coli |
| assay ≥70% (SDS-PAGE) | assay ≥70% (SDS-PAGE) | assay ≥80% (SDS-PAGE) | assay ≥85% (SDS-PAGE) |
| form buffered aqueous glycerol solution | form buffered aqueous glycerol solution | form frozen liquid | form frozen liquid |
| mol wt ~63 kDa | mol wt ~96 kDa | mol wt ~60 kDa | mol wt ~77.3 kDa |
| NCBI accession no. | NCBI accession no. | NCBI accession no. | NCBI accession no. |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in dry ice |
Descripción general
ATF1 is a class of transcription factor that stimulates gene expression of several cell growth-related genes through protein kinase A-related cAMP response elements. ATF1 can physically associate with BRCA1 in vitro, in yeast, and in human cells and BRCA1 is implicated in the transcriptional activation of ATF1 target genes, some of which are involved in the transcriptional response to DNA damage. Mitogen- and stress-activated protein kinase 1 (MSK1) and MSK2 play a role in the stress-induced phosphorylation of ATF1 in primary embryonic fibroblasts. However, mitogen-induced phosphorylation of ATF1 is greatly reduced.
Forma física
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Nota de preparación
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
Código de clase de almacenamiento
10 - Combustible liquids
WGK
WGK 1
Punto de inflamabilidad F
Not applicable
Punto de inflamabilidad C
Not applicable
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Certificate of Origin
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Data Sheets
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