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SRP5201

Sigma-Aldrich

KAT9, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):
FLJ10422
NACRES:
NA.32

recombinante

expressed in baculovirus infected Sf9 cells

ensayo

≥70% (SDS-PAGE)

formulario

buffered aqueous glycerol solution

mol peso

~86 kDa

Nº de acceso NCBI

enviado en

dry ice

temp. de almacenamiento

−70°C

Gene Information

human ... ELP3(55140)

Descripción general

KAT9 (also known as ELP3) is the catalytic subunit of the histone acetyltransferase (HAT) elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons. The knockdown of KAT9 by antisense morpholinos in zebrafish embryos resulted in dose-dependent shortening and abnormal branching of motor neurons with no concomitant morphologic abnormalities. KAT9 knockdown also impairs paternal DNA demethylation as indicated by reporter binding, immunostaining, and bisulfite sequencing.

Forma física

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Nota de preparación

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 1

Certificate of Analysis

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Certificate of Origin

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