Merck
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SRP5219

Sigma-Aldrich

KAT3A (518-1207), GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):
CBP, CREBBP, KAT3A, RSTS
CAS Number:
NACRES:
NA.32

origen biológico

human

recombinante

expressed in baculovirus infected Sf9 cells

ensayo

≥70% (SDS-PAGE)

formulario

buffered aqueous glycerol solution

mol peso

~140 kDa

Nº de acceso NCBI

application(s)

cell analysis

enviado en

dry ice

temp. de almacenamiento

−70°C

Gene Information

human ... CREBBP(1387)

Acciones bioquímicas o fisiológicas

KAT3A has intrinsic histone acetyltransferase activity that acts as a scaffold to stabilize additional protein interactions with the transcription complex and acetylates both histone and non-histone proteins. KAT3A (CREBBP) expressed as a nuclear protein that binds to cAMP-response element binding protein (CREB) and involved in the transcriptional coactivation of many different transcription factors. KAT3A plays a main role in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. KAT3A also plays a critical role in the transmission of inductive signals from cell surface receptors to the transcriptional apparatus.

Forma física

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

Nota de preparación

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 1

Certificate of Analysis

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Certificate of Origin

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SDS

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