Merck
All Photos(2)

SRP5265

Sigma-Aldrich

HDAC1, active, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):
DKFZp686H12203, GON-10, HD1, RPD3, RPD3L1
NACRES:
NA.32

recombinante

expressed in baculovirus infected Sf9 cells

ensayo

≥70% (SDS-PAGE)

formulario

buffered aqueous glycerol solution

specific activity

7565-11765 RLU/min·ng

mol peso

~88 kDa

Nº de acceso NCBI

enviado en

dry ice

temp. de almacenamiento

−70°C

Gene Information

human ... HDAC1(3065)

Descripción general

HDAC1 or Histone deacetylase 1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex which plays a key role in the regulation of eukaryotic gene expression. HDAC1 interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis. HDAC1 is an essential element of the co-activation system for IFN-induced gene regulation and antiviral responses.

Forma física

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Nota de preparación

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

SDS

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service