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SRP5318

Sigma-Aldrich

TYK2 (JTK1), active, GST tagged human

PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):
MGC126760, MGC126762, PSCTK4
NACRES:
NA.32

recombinante

expressed in baculovirus infected Sf9 cells

línea de producto

PRECISIO®

ensayo

≥70% (SDS-PAGE)

formulario

buffered aqueous glycerol solution

specific activity

19.2-28.8 nmol/min·mg

mol peso

~110 kDa

Nº de acceso NCBI

enviado en

dry ice

temp. de almacenamiento

−70°C

Gene Information

human ... TYK2(7297)

Descripción general

TYK2 is a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families which associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. TYK2 play a role in anti-viral immunity and TYK2 plays an indispensable role in controlling responses to multiple cytokines in humans. Tyk2 contributes selectively to signals triggered by various biologic stimuli and cytokine receptors and TYK2 is an important regulator of lymphoid tumor surveillance.

Forma física

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Nota de preparación

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.

Información legal

PRECISIO is a registered trademark of Sigma-Aldrich Co. LLC

Código de clase de almacenamiento

10 - Combustible liquids

WGK

WGK 1

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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