Merck
All Photos(1)

SRP6017

Sigma-Aldrich

IL-19 from mouse

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

Synonym(s):
IL-10C, MDA1, Melanoma differentiation association like protein, NG.1, ZMDA1
CAS Number:
NACRES:
NA.32

origen biológico

mouse

recombinante

expressed in E. coli

ensayo

≥95% (HPLC)
≥95% (SDS-PAGE)

formulario

lyophilized

mol peso

17.7 kDa

envase

pkg of 10 μg

impurezas

Endotoxin, tested

Nº de acceso NCBI

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

mouse ... IL19(329244)

Descripción general

IL19 (interleukin 19) belongs to the IL-10 family of cytokines, and shares high homology with IL-20 and IL-24 at the primary level. It is further subcategorized into a subfamily containing IL-19, IL-20, and IL-24. It was first discovered in 2001, and its expression is not only limited to leukocytes and is also expressed by angiogenic tissue.

Acciones bioquímicas o fisiológicas

IL19 (interleukin 19) promotes the production of pro-inflammatory cytokines, such as IL-6 and TNF-α, and therefore, participates in the pathogenesis of autoimmune diseases such as psoriasis, asthma, and rheumatoid arthritis. This protein functions as a strong pro-angiogenic influence on different human EC (endothelial cell) types, such as umbilical vein, coronary artery, and microvascular types. In Th2 (T helper)-mediated colitis rat model IL-19 functions as an anti-inflammatory agent, and might have potential as a therapeutic target for alleviating colonic inflammation.

Forma física

Sterile filtered and lyophilized with no additives

Reconstitución

Centrifuge the vial prior to opening. Reconstitute in H?O to a concentration of 0.1-0.5 mg/ml. The solution can be diluted into other aqueous buffers

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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