IL-19 reduces ligation-mediated neointimal hyperplasia by reducing vascular smooth muscle cell activation.
Ellison S et al
The American Journal of Pathology, 184(7), 2134-2143 (2014)
Interleukin-19 contributes as a protective factor in experimental Th2-mediated colitis.
Fujimoto Y et al
Naunyn-Schmiedeberg'S Archives of Pharmacology, 390(3), 261-268 (2017)
Michelle L Manni et al.
Journal of immunology (Baltimore, Md. : 1950), 196(3), 963-977 (2016-01-06)
IL-13 and IL-17A, produced mainly by Th2 and Th17 cells, respectively, have an influential role in asthma pathogenesis. We examined the role of IL-13 and IL-17A in mediating airway hyperresponsiveness (AHR), lung inflammation, and mucus metaplasia in a dual Th2/Th17...
Carol Hoffman et al.
PloS one, 6(11), e27629-e27629 (2011-11-24)
Interleukin (IL)-19 has been reported to enhance chronic inflammatory diseases such as asthma but the in vivo mechanism is incompletely understood. Because IL-19 is produced by and regulates cells of the monocyte lineage, our studies focused on in vivo responses...
James Richards et al.
Journal of molecular and cellular cardiology, 79, 21-31 (2014-12-03)
Hypoxia in ischemic limbs typically initiates angiogenic and inflammatory factors to promote angiogenesis in attempt to restore perfusion. There is a gap in our knowledge concerning the role of anti-inflammatory interleukins in angiogenesis, macrophage polarization, and endothelial cell activation. Interleukin-19...