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Proteinase 3 from human neutrophils

≥95% (SDS-PAGE)

Leukocyte proteinase 3, Neutrophil proteinase 4, P29, C-ANCA antigen, AGP7, Wegener autoantigen

origen biológico



≥95% (SDS-PAGE)


frozen liquid

mol peso

29 kDa


pkg of 25 μg

Nº de acceso UniProt

enviado en

dry ice

temp. de almacenamiento


Gene Information

human ... AGP7(5657)

Related Categories

Descripción general

Proteinase 3 is one of the serine proteinases localized in azurophil granules of polymorphonuclear leukocytes. It has been identified as the autoantigen of Wegener granulomatosis, a systemic vasculitis complicated by melomonocyte proliferation. It exhibits proteolytic activity towards a range of substrates. It is physiologically inhibited by α1-antitrypsin. The protein has been described as having antibiotic and growth-promoting properties and causing emphysema when administered by tracheal insufflation. Proteinase 3 (PR-3) is also known as myeloblastin and p29b.

Forma física

Frozen in 50 mM MES, pH 4.5 with 700 mM NaCl.

Código de clase de almacenamiento

11 - Combustible Solids



Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

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