All Photos(1)
SRP6309
Proteinase 3 from human neutrophils
≥95% (SDS-PAGE)
All Photos(1)
Synonym(s):
Leukocyte proteinase 3, Neutrophil proteinase 4, P29, C-ANCA antigen, AGP7, Wegener autoantigen
origen biológico
human
ensayo
≥95% (SDS-PAGE)
formulario
frozen liquid
mol peso
29 kDa
envase
pkg of 25 μg
Nº de acceso UniProt
enviado en
dry ice
temp. de almacenamiento
−70°C
Gene Information
human ... AGP7(5657)
Related Categories
Descripción general
Proteinase 3 is one of the serine proteinases localized in azurophil granules of polymorphonuclear leukocytes. It has been identified as the autoantigen of Wegener granulomatosis, a systemic vasculitis complicated by melomonocyte proliferation. It exhibits proteolytic activity towards a range of substrates. It is physiologically inhibited by α1-antitrypsin. The protein has been described as having antibiotic and growth-promoting properties and causing emphysema when administered by tracheal insufflation. Proteinase 3 (PR-3) is also known as myeloblastin and p29b.
Forma física
Frozen in 50 mM MES, pH 4.5 with 700 mM NaCl.
Código de clase de almacenamiento
11 - Combustible Solids
WGK
nwg
Punto de inflamabilidad F
Not applicable
Punto de inflamabilidad C
Not applicable
Certificate of Analysis
Enter Lot Number to search for Certificate of Analysis (COA).
Certificate of Origin
Enter Lot Number to search for Certificate of Origin (COO).
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service