Merck
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SRP6381

Sigma-Aldrich

CD244/2B4/SLAMF4 human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

Synonym(s):
NAIL, NKR2B4, h2B4
NACRES:
NA.32

origen biológico

human

recombinante

expressed in HEK 293 cells

etiqueta

6-His tagged (C-terminus)

ensayo

≥95% (SDS-PAGE)

formulario

lyophilized

mol peso

calculated mol wt 23.1 kDa
observed mol wt 40-50 kDa (DTT-reduced. Protein migrates due to glycosylation. Cys 22 is the predicted N-terminus.)

envase

pkg of 10 μg
pkg of 50 μg

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

human ... CD244(51744)

Descripción general

Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contain two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.

Forma física

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitución

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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