SRP6419

Sigma-Aldrich

Kallikrein-13 human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

Sinónimos:
KLK-13, KLK13, KLKL4
En este momento no podemos mostrarle ni los precios ni la disponibilidad

biological source

human

recombinant

expressed in HEK 293 cells

assay

≥95% (SDS-PAGE)

form

lyophilized

mol wt

calculated mol wt 28 kDa
observed mol wt 33-40 kDa by SDS-PAGE (DTT-reduced. Protein migrates due to glycosylation. Gly 18 is the predicted N-terminal.)

packaging

pkg of 10 μg

conjugate

6-His tagged (C-terminus)

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... KLK13(26085)

General description

Kallikrein-13 (KLK13) is also known as Kallikrein-like protein 4 (KLK-L4), is a secreted protein, belongs to the peptidase S1 family and Kallikrein subfamily. KLK-13 contains one peptidase S1 domain. KLK13 is mainly expressed in prostate, breast, testis and salivary gland. KLK13 may be involved in the pathogenesis and / or progression of breast and ovary cancers, and is regarded as a novel cancer biomarker. In addition, KLK13 interacts and forms complexes with several serum protease inhibitors, such as α2-macroglobulin, and its expression is regulated by steroid hormones.

Physical form

Lyophilized from 0.22 μm filtered solution in 20 mM MES, 150 mM NaCl, pH 6.0. Normally Mannitol or Trehalose are added as protectants before lyophilization.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point F

Not applicable

Flash Point C

Not applicable

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