Merck
All Photos(1)

SRP8035

Sigma-Aldrich

IL-36α mouse

recombinant, expressed in E. coli, untagged, >95% (SDS-PAGE)

Synonym(s):
Interleukin-1 family member 6, Interleukin-1 homolog 1, Interleukin-1α, Interleukin-36α
NACRES:
NA.32

origen biológico

mouse

recombinante

expressed in E. coli

conjugado

untagged

ensayo

>95% (SDS-PAGE)

formulario

lyophilized

mol peso

~17 kDa

envase

pkg of 10 μg

impurezas

<0.01 EU/μg endotoxin, tested

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

mouse ... Il36a(54448)

Descripción general

IL-36α (IL-1F6), IL-36β (IL-1F8) and IL-36γ (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1β, IL-6, TNF-α and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

Forma física

Lyophilized from PBS.

Reconstitución

Reconstitute with 100 μL deionized water.

Otras notas

IL-36alpha (mouse) (aa 8-160) is untagged.

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

WGK 2

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service