Merck
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T1698

Sigma-Aldrich

Tetradecylthioacetic acid

≥97% (NMR)

Synonym(s):
TTA
Linear Formula:
C14H29-S-CH2COOH
CAS Number:
Molecular Weight:
288.49
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

≥97% (NMR)

color

white

solubilidad

DMSO: soluble ≥22 mg/mL

SMILES string

CCCCCCCCCCCCCCSCC(O)=O

InChI

1S/C16H32O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-19-15-16(17)18/h2-15H2,1H3,(H,17,18)

InChI key

IPBCWPPBAWQYOO-UHFFFAOYSA-N

Gene Information

human ... PPARA(5465)

Envase

5 mg in glass bottle
Packaged under nitrogen.

Acciones bioquímicas o fisiológicas

Tetradecylthioacetic acid (TTA) is known to modulate lipid homeostasis. TTA can increase fatty acid oxidation and ketogenesis, which can subsequently prevent adiposity and insulin resistance. Furthermore, TTA can enhance cardiac functions during experimental heart failure.
PPARα agonist; activation in ranking order: PPARδ > PPARα > PPARγ

Características y beneficios

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Nota de preparación

Tetradecylthioacetic acid is soluble in DMSO at a concentration that is greater than or equal to 22 mg/ml.

Certificate of Analysis

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Certificate of Origin

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