T3526

Anti-Tubulin antibody produced in rabbit

whole antiserum

• Synonym(s): Anti-K-ALPHA-1
• Número MDL: MFCD00145921
• NACRES: NA.41

Properties

• origen biológico: rabbit
• Nivel de calidad: 200
• conjugado: unconjugated
• forma del anticuerpo: whole antiserum
• antibody product type: primary antibodies
• clon: polyclonal
• contiene: 15 mM sodium azide
• species reactivity: chicken, mouse
• technique(s): indirect immunofluorescence: 1:80 using cultured fibroblasts; western blot: 1:200 using chicken gizzard extract or mouse brain extract
• Nº de acceso UniProt: P68363
• enviado en: dry ice
• temp. de almacenamiento: −20°C
• Gene Information: mouse ... Tuba1b(22143) , Tubb2a(22151) , Tubb2b(73710) , Tubb2c(227613)

Description

Descripción general

Microtubules are composed of tubulin and several additional proteins designated microtubule associated proteins (MAPs). Tubulin is a heterodimer which consists of an α-chain and a β-chain, both of which have a molecular weight of approximately 55,000. Microtubules form an elaborate cytoplasmic network during interphase and are reorganized into the mitotic spindle during cell division.

Tubulin is an extremely conserved and negatively charged protein. It is expressed in all eukaryotic cells, but mainly in brains.

Especificidad

The product stains tubulin in cultured chicken fibroblasts or 3T3 mouse fibroblasts. Additional bands may be stained in immunoblotting.

Inmunógeno

microtubule proteins from brains of 13 day old chicken embryos

Aplicación

Anti-Tubulin antibody produced in rabbit has been used in immunoblotting and indirect immunofluorescence.

Acciones bioquímicas o fisiológicas

αβ-tubulin heterodimers helps in formation of microtubules. Tubulin dimers exhibits GTPase activity, assembly and disassembly properties. It facilitates the construction of the flagellar apparatus.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Código de clase de almacenamiento: 12 - Non Combustible Liquids
• WGK: WGK 3
• Punto de inflamabilidad F: Not applicable
• Punto de inflamabilidad C: Not applicable
• Equipo de protección personal: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)