T5823

Sigma-Aldrich

Anti-TCCR, C-Terminal antibody produced in rabbit

~0.5 mg/mL, affinity isolated antibody, buffered aqueous solution

Sinónimos:
Anti-WSX-1, Anti-T-Cell Cytokine Receptor
MDL number:
En este momento no podemos mostrarle ni los precios ni la disponibilidad

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~70 kDa

species reactivity

rat, mouse, human

concentration

~0.5 mg/mL

application(s)

western blot: 0.5-1 μg/mL

conjugate

unconjugated

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... IL27RA(9466)
mouse ... Il27ra(50931)
rat ... Il27ra(288905)

Immunogen

synthetic peptide corresponding to amino acids 611-625 of human TCCR precursor.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

RIDADR

NONH for all modes of transport

Flash Point F

Not applicable

Flash Point C

Not applicable

Q Chen et al.
Nature, 407(6806), 916-920 (2000-11-01)
On antigen challenge, T-helper cells differentiate into two functionally distinct subsets, Th1 and Th2, characterized by the different effector cytokines that they secrete. Th1 cells produce interleukin (IL)-2, interferon-gamma (IFN-gamma) and lymphotoxin-beta, which mediate pro-inflammatory functions critical for the development...
Que T Lambert et al.
The Biochemical journal, 438(1), 155-164 (2011-06-03)
Cytokines and their receptors regulate haemopoiesis by controlling cellular growth, survival and differentiation. Thus it is not surprising that mutations of cytokine receptors contribute to the formation of haemopoietic disorders, including cancer. We recently identified transforming properties of IL27R, the...
Anuradha Pradhan et al.
The Journal of biological chemistry, 285(22), 16651-16663 (2010-04-07)
The JAK2-V617F mutation is an important etiologic factor for the development of myeloproliferative neoplasms. The mechanism by which this mutated tyrosine kinase initiates deregulated signals in cells is not completely understood. It is believed that JAK2-V617F requires interactions with homodimeric...

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