Merck
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T7329

Sigma-Aldrich

Taurolidine

>97% (NMR), powder

Synonym(s):
Tauroline, 4,4′-Methylenebis(tetrahydro-1,2,4-sulfadiazine 1,1-dioxide), Taurolin
Empirical Formula (Hill Notation):
C7H16N4O4S2
CAS Number:
Molecular Weight:
284.36
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

100

ensayo

>97% (NMR)

formulario

powder

condiciones de almacenamiento

protect from light

color

white to off-white

solubilidad

DMSO: >20 mg/mL

temp. de almacenamiento

room temp

SMILES string

O=S1(=O)CCN(CN1)CN2CCS(=O)(=O)NC2

InChI

1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2

InChI key

AJKIRUJIDFJUKJ-UHFFFAOYSA-N

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Envase

5, 25 mg in glass bottle

Acciones bioquímicas o fisiológicas

Taurolidine is a broad spectrum antibiotic with antineoplastic activity, which induces apoptosis and decreases tumor cell proliferation. Taurolidine has been used with TNF-related-apoptosis-inducing ligand (TRAIL) to characterize synergistic responses in many apoptosis related signaling-proteins. Tauroline is also being used as a tool to study the various mechanisms of apoptosis and necrosis.
Taurolidine is an antibacterial agent that can be used for the treatment of peritonis. It has also been used as an antiendoxic substance for systematic inflammatory response syndrome and as an anti-angiogenic agent for tumors. Furthermore, studies have reported that taurolidine can be used for the prevention of multiple catheter-related bloodstream infections.

Nota de preparación

Taurolidine is soluble in DMSO at a concentration that is greater than 20 mg/ml.

Código de clase de almacenamiento

11 - Combustible Solids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Certificate of Analysis

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Certificate of Origin

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