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T7444

Sigma-Aldrich

Anti-phospho-Tau (pSer404) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Número MDL:
NACRES:
NA.41

origen biológico

rabbit

Nivel de calidad

200

conjugado

unconjugated

forma del anticuerpo

affinity isolated antibody

antibody product type

primary antibodies

clon

polyclonal

formulario

buffered aqueous glycerol solution

species reactivity

mouse, human, rat

technique(s)

immunohistochemistry: suitable
western blot: 1:1,000

Nº de acceso UniProt

enviado en

wet ice

temp. de almacenamiento

−20°C

Gene Information

human ... MAPT(4137)
mouse ... Mapt(17762)
rat ... Mapt(29477)

Descripción general

Tau is a microtubule-associated phosphoprotein that is present in the axons of nerve cells. It stabilizes microtubules and mediates the polymerization of tubulin. Phosphorylation of Tau regulates its cellular functions. Hyperphosphorylation of Tau has been linked to neurodegenerative disorders such as Alzheimer′s disease . Anti-phospho-Tau (pSer404) antibody specifically reacts with Tau (pSer404) (45-68 kDa) in humans, mice and rats.

Inmunógeno

chemically synthesized phosphopeptide derived from the region of human tau that contains serine404.

Aplicación

Anti-phospho-Tau (pSer404) antibody may be used in western blot (1:1000), immunoblot (1:1000) and immunohistochemistry.

Forma física

Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, with 50% glycerol, 1.0 mg/ml BSA (IgG and protease free) and 0.05% sodium azide.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Código de clase de almacenamiento

12 - Non Combustible Liquids

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

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Certificate of Origin

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