Immunoglobulin G (IgG)antibody is found in four subclasses IgG1, IgG2, IgG3 and IgG4. It has a monomeric structure. IgG is secreted by B cells and is found in blood and extracellular fluids.. Anti-Mouse IgG (Fab specific) is conjugated to tetramethylrhodamine isothiocyanate (TRITC) and then purified by gel filtration to remove free TRITC.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Conjugation of TRITC to Mouse IgG (Fab specific) antibody enables the use in immunofluorescent techniques.
Acciones bioquímicas o fisiológicas
Immunoglobulin G (IgG) antibody participates in complement fixation and opsonization.
IgG antibody subtype provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Antibody adsorbed with bovine, equine and human serum proteins.
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Nota de preparación
Adsorbed to reduce background staining with bovine, horse or human samples.
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