T7883
200
≥98% (HPLC)
powder
(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
white to off-white
chloroform/ethanol (1:1): soluble 50 mg/mL
DMSO: soluble
Gram-negative bacteria
Gram-positive bacteria
mycobacteria
DNA synthesis | interferes
enzyme | inhibits
2-8°C
COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
IEDVJHCEMCRBQM-UHFFFAOYSA-N
human ... DHFRP1(573971) , KCNH1(3756)
rat ... Dhfr(24312)
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Danger
Acute Tox. 3 Oral - Repr. 2
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK 3
Not applicable
Not applicable
Eyeshields, Gloves, type N95 (US)
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Triemethoprim in a solution of 52% N,N dimethylacetamide:48% propylene glycol at 50 mg/ml is stable when stored at 25° C. There is only a 10% degradation of trimethoprim under these conditions after 885 days.
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