Merck
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U0881

Sigma-Aldrich

Uric acid

BioXtra, ≥99% (HPLC)

Sinónimos:
2,6,8-Trihydroxypurine
Empirical Formula (Hill Notation):
C5H4N4O3
Número de CAS:
Peso molecular:
168.11
Beilstein:
156158
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.55

Nivel de calidad

200

origen biológico

animal (seabird feces (guano))

línea de producto

BioXtra

ensayo

≥99% (HPLC)

formulario

powder

impurezas

≤0.005% Phosphorus (P)

residuo de ign.

≤0.1%

mp

>300 °C (lit.)

solubilidad

1 M NaOH: soluble 50 mg/mL, clear, faintly yellow

trazas de catión

Al: ≤0.005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.05%
Mg: ≤0.001%
NH4+: ≤0.05%
Na: ≤0.1%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)

InChI key

LEHOTFFKMJEONL-UHFFFAOYSA-N

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Categorías relacionadas

Código de clase de almacenamiento

13 - Non Combustible Solids

WGK

WGK 2

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificado de Análisis

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Certificado de origen

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Christine Schauer et al.
Nature medicine, 20(5), 511-517 (2014-05-03)
Gout is characterized by an acute inflammatory reaction and the accumulation of neutrophils in response to monosodium urate (MSU) crystals. Inflammation resolves spontaneously within a few days, although MSU crystals can still be detected in the synovial fluid and affected
Pierre Guermonprez et al.
Nature medicine, 19(6), 730-738 (2013-05-21)
Innate sensing mechanisms trigger a variety of humoral and cellular events that are essential to adaptive immune responses. Here we describe an innate sensing pathway triggered by Plasmodium infection that regulates dendritic cell homeostasis and adaptive immunity through Flt3 ligand
Francesca Viazzi et al.
Pediatrics, 132(1), e93-e99 (2013-06-19)
Hyperuricemia has been shown to be a strong correlate of hypertension in children. However, the complex interaction between serum uric acid (UA), systemic blood pressure (BP), and possibly confounding factors has been elucidated only in part. We evaluated office BP
Ashika Chhana et al.
Annals of the rheumatic diseases, 73(9), 1737-1741 (2014-04-09)
Advanced imaging studies have demonstrated that urate deposition in periarticular structures, such as tendons, is common in gout. The aim of this study was to investigate the effects of monosodium urate monohydrate (MSU) crystals on tenocyte viability and function. The
Tom M Palmer et al.
BMJ (Clinical research ed.), 347, f4262-f4262 (2013-07-23)
To assess the associations between both uric acid levels and hyperuricaemia, with ischaemic heart disease and blood pressure, and to explore the potentially confounding role of body mass index. Mendelian randomisation analysis, using variation at specific genes (SLC2A9 (rs7442295) as

Artículos

Uric Acid in Cell Culture

Uric acid is not a direct additive to any of the classical cell culture media. However, it is present in animal sera. Consequently, uric acid is typically present in complete serum-supplemented classical cell culture systems.

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