V1628

Sigma-Aldrich

Verrucarol

Sinónimos:
4β,15-Dihydroxy-12,13-epoxytrichothec-9-ene
Empirical Formula (Hill Notation):
C15H22O4
Número de CAS:
Peso molecular:
266.33
MDL number:
PubChem Substance ID:
NACRES:
NA.77
En este momento no podemos mostrarle ni los precios ni la disponibilidad

Quality Level

storage temp.

−20°C

SMILES string

HC@12CC@@H(O)C(C)(C@@3(CO)CCC(C)=CC@@3(H)O1)C24CO4

InChI

1S/C15H22O4/c1-9-3-4-14(7-16)11(5-9)19-12-6-10(17)13(14,2)15(12)8-18-15/h5,10-12,16-17H,3-4,6-8H2,1-2H3/t10-,11-,12-,13?,14-,15?/m1/s1

InChI key

ZSRVBNXAPSQDFY-CXOCQXMISA-N

Packaging

1 mg in glass bottle

Biochem/physiol Actions

Trichothecene mycotoxin that is a component of toxic mold. Esters of verrucarol have anti-tumor activity.

pictograms

Skull and crossbones

signalword

Danger

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

T+

Risk Statement

26/27/28-36/37/38

Safety Statement

22-26-36/37/39-45

RIDADR

UN 2811 6.1 / PGI

WGK Germany

WGK 3

P F Schuda et al.
Journal of natural products, 47(3), 514-519 (1984-05-01)
4-Deoxyverrucarol (4) has been synthesized for use in studies for the preparation and development of monoclonal antibodies for trichothecenes. Both verrucarol (1) and anguidine (2) have been converted to deoxyverrucarol (DOVE) (4) by deoxygenation at C3 and at C3 and...
M Gareis et al.
Tierarztliche Praxis. Supplement, 1, 8-19 (1985-01-01)
Mycotoxicoses have been recognized worldwide to cause problems in animal production. Trichothecene mycotoxins, for the most part produced by Fusarium spp., have obtained particular importance. Between 1982 and 1984, 295 samples of feedstuffs (cereals and mixed feeds) have been analyzed...
T Tuomi et al.
Applied and environmental microbiology, 66(5), 1899-1904 (2000-05-02)
We analyzed 79 bulk samples of moldy interior finishes from Finnish buildings with moisture problems for 17 mycotoxins, as well as for fungi that could be isolated using one medium and one set of growth conditions. We found the aflatoxin...
F S Chu et al.
Applied and environmental microbiology, 48(4), 781-784 (1984-10-01)
Immunization of rabbits with deoxyverrucarol (DOVE) conjugated to bovine serum albumin resulted in antibodies bound with either tritiated DOVE or diacetoxyscirpenol (DAS), but not with T-2 toxin. The affinity of antibodies with DOVE was found to be much higher than...
Mirko Peitzsch et al.
Journal of environmental monitoring : JEM, 14(3), 908-915 (2012-01-31)
We compared the efficiency of some commercially available products and methods used for remediation of mould-contaminated building materials. Samples of gypsum board and pinewood were artificially contaminated with toxin-producing isolates of Stachybotrys chartarum and Aspergillus versicolor, respectively, then, ten different...

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