V5140

VPS34 human

recombinant, expressed in Sf9 cells

• Sinónimos: VPS34 human
• NACRES: NA.54

Propiedades

• Quality Level: 200
• recombinant: expressed in Sf9 cells
• form: liquid
• specific activity: ≥100 units/μg protein
• mol wt: 98.2 kDa
• NCBI accession no.: NM_002647
• shipped in: dry ice
• storage temp.: −70°C

Descripción

General description

This Human VPS34 (vacuolar protein sorting 34) protein has a N-terminal FLAG-tag, expressed in Sf9 insect cells via a baculovirus expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Biochem/physiol Actions

VPS34 was shown to be required for proper liver and heart function. Mice deficient in VPS34 develop hepatomegaly and cardiomegaly.

Unit Definition

One unit will transfer one picomole of phosphate from ATP to a phospholipid mixture per minute at 30 °C at pH 7.4.

Physical form

Formulated in a buffered solution consisting of 40 mM tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 μg/ml FLAG peptide, and 20% glycerol.

Información de seguridad

• RIDADR: NONH for all modes of transport
• WGK Germany: WGK 1
• Flash Point F: Not applicable
• Flash Point C: Not applicable