Todas las fotos(1)

X1126

Sigma-Aldrich

Xylazine

≥99%

Sinónimos:
2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine
Empirical Formula (Hill Notation):
C12H16N2S
Número de CAS:
Peso molecular:
220.33
Número de EC:
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.77

Nivel de calidad

200

ensayo

≥99%

temp. de almacenamiento

−20°C

SMILES string

Cc1cccc(C)c1NC2=NCCCS2

InChI

1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)

InChI key

BPICBUSOMSTKRF-UHFFFAOYSA-N

Descripción general

Xylazine is soluble in methanol (50 mg/ml), yielding a clear, colorless solution. It is also soluble in dilute HCl acid and in chloroform. Xylazine is practically insoluble in water and in alkali solutions.

Aplicación

Xylazine has been used to anaesthetise experimental animals.

Acciones bioquímicas o fisiológicas

Xylazine when used along with ketamine is considered to be a potent and safe anaesthetic in experimental animal. It is known to elevate the hepatic release of glucose, which aggravates to hyperglycemia.
α2-adrenoceptor agonist, sedative, muscle relaxant.

Otras notas

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. X1126.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

pictogramas

Skull and crossbones

Palabra de señalización

Danger

Frases de peligro

Consejos de prudencia

Clasificaciones de peligro

Acute Tox. 3 Oral

Código de clase de almacenamiento

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Punto de inflamabilidad F

Not applicable

Punto de inflamabilidad C

Not applicable

Equipo de protección personal

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificado de Análisis

Certificado de origen

MIND model for triple-negative breast cancer in syngeneic mice for quick and sequential progression analysis of lung metastasis
Ghosh A, et al.
PLoS ONE, 13(5), e0198143-e0198143 (2018)
Acute reversible cataract induced by xylazine and by ketamine-xylazine anesthesia in rats and mice
Calderone L, et al.
Experimental Eye Research, 42(4), 331-337 (1986)
Lactobacillus casei addition to a repletion diet-induced early normalisation of cytokine profils during a pneumococcal infection in malnourished mice
Salva S, et al.
Food and agricultural immunology, 19(3), 195-211 (2008)
Imaging of rat optic nerve axons in vivo
Koch JC, et al.
Nature Protocols, 6(12), 1887-1887 (2011)
Hannah T Nickles et al.
American journal of physiology. Lung cellular and molecular physiology, 307(1), L27-L37 (2014-05-13)
The pathogenesis of ventilator-induced lung injury has predominantly been attributed to overdistension or mechanical opening and collapse of alveoli, whereas mechanical strain on the airways is rarely taken into consideration. Here, we hypothesized that mechanical ventilation may cause significant airway

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