Merck

1005706

USP

Ácido acético

United States Pharmacopeia (USP) Reference Standard

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Sinónimos:
Ácido acético glacial
Fórmula lineal:
CH3CO2H
Número de CAS:
Peso molecular:
60.05
Beilstein:
506007
Número MDL:
ID de la sustancia en PubChem:
NACRES:
NA.24

grado

pharmaceutical primary standard

densidad de vapor

2.07 (vs air)

API family

glacial acetic acid

temp. de autoignición

800 °F

lim. expl.

16 %, 92 °F
4 %, 59 °F

manufacturer/tradename

USP

technique(s)

gas chromatography (GC): suitable

índice de refracción

n20/D 1.371 (lit.)

bp

117-118 °C (lit.)

mp

16.2 °C (lit.)

densidad

1.049 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

formato

neat

SMILES string

CC(O)=O

InChI

1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

InChI key

QTBSBXVTEAMEQO-UHFFFAOYSA-N

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Este artículo
PHR1748137130
Glacial acetic acid United States Pharmacopeia (USP) Reference Standard

USP

1005706

Glacial acetic acid

Glacial Acetic Acid Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1748

Glacial Acetic Acid

Acetic acid, glacial EMPROVE® EXPERT, Ph. Eur., JP, USP

SAFC

137130

Acetic acid, glacial

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

format

neat

format

neat

format

-

vapor density

2.07 (vs air)

vapor density

2.07 (vs air)

vapor density

2.07 (vs air)

API family

glacial acetic acid

API family

glacial acetic acid

API family

-

Descripción general

Glacial acetic acid is the trivial name used to describe pure acetic acid in an anhydrous state. It is a clear and hygroscopic weak acid, typically available in concentrations ranging from 99.5% to 100%. The name "glacial" refers to the ice-like crystals that form at a temperature slightly below room temperature (16.6°C or 61.9°F), like the German term "Eisessig" (ice-vinegar). Despite being classified as a weak acid, glacial acetic acid is a corrosive poison that can cause harm or even be fatal when in contact with human tissue. Improper storage and handling of glacial acetic acid can pose inherent risks and may lead to patient injuries if not appropriately diluted. Acetic acid/acetate is a common counter ion in peptide preparations.
Glacial acetic acid USP reference standard is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Glacial acetic acid USP reference standard for use in specified quality tests and assays. It is also used to prepare standard solution by using liquid chromatography coupled to a UV detector according to the general chapter of United States Pharmacopeia (USP). Based directly on official monographs published in the USP-NF, these highly characterized physical specimens are used in testing by pharmaceutical and related industries to help ensure the identity, strength, quality, and purity of peptide-based medicines.
Further information is available in the general chapter, ?503? ACETIC ACID IN PEPTIDES, USP43-NF38 - 6741 of the USP (United States Pharmacopeia).
Glacial acetic acid USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solution by using liquid chromatography coupled to a UV detector according to the monograph of United States Pharmacopeia (USP).

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

This product is intended for use as a reference standard in pharmaceutical research and development. It is not tested for animal or human consumption, clinical testing, or therapeutic use.
Sales restrictions may apply.

Producto relacionado

Referencia del producto
Descripción
Precios

Pictogramas

FlameCorrosion

Palabra de señalización

Danger

Frases de peligro

Clasificaciones de peligro

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

Código de clase de almacenamiento

3 - Flammable liquids

Clase de riesgo para el agua (WGK)

WGK 1

Punto de inflamabilidad (°F)

102.2 °F

Punto de inflamabilidad (°C)

39 °C


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Acetic acid glacial, ≥99.99% trace metals basis

Sigma-Aldrich

338826

Acetic acid

Acetic acid glacial, ACS reagent, ≥99.7%

Sigma-Aldrich

695092

Acetic acid

Acetic acid in peptides
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(5), 6741-6741 (2017)
Glacial Acetic Acid Adverse Events: Case Reports and Review of the Literature
Doles W, et al.
Hospital pharmacy (2015)
ACETIC ACID IN PEPTIDES
USP43-NF38 - 6741:United States Pharmacopeia and National Formulary
United States Pharmacopeia, 42(5) (2017)
Ilse Cleenwerck et al.
International journal of food microbiology, 125(1), 2-14 (2008-02-02)
Acetic acid bacteria are Gram-negative, obligate aerobic bacteria that have the ability to incompletely oxidize alcohols or sugars to organic acids as end products. They are widespread in nature and most of them are capable to oxidize ethanol as substrate
Katharine Trenholme et al.
Antimicrobial agents and chemotherapy, 58(7), 3666-3678 (2014-04-16)
Therapies to prevent transmission of malaria parasites to the mosquito vector are a vital part of the global malaria elimination agenda. Primaquine is currently the only drug with such activity; however, its use is limited by side effects. The development

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