1134368

Ácido cítrico

United States Pharmacopeia (USP) Reference Standard

• Fórmula lineal: HOC(COOH)(CH₂COOH)₂
• Número CAS: 77-92-9
• Peso molecular: 192.12
• UNSPSC Code: 41116107
• NACRES: NA.24
• PubChem Substance ID: 329749410
• MDL number: MFCD00011669
• Beilstein/REAXYS Number: 782061

Propiedades

• InChI: 1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• SMILES string: OC(=O)CC(O)(CC(O)=O)C(O)=O
• InChI key: KRKNYBCHXYNGOX-UHFFFAOYSA-N
• grade: pharmaceutical primary standard
• API family: citric acid
• form: crystalline
• expl. lim.: 8 %, 65 °F
• manufacturer/tradename: USP
• pKa: (1) 3.13, (2) 4.76, (3) 6.4
• mp: 153-159 °C (lit.)
• solubility: water: 383 g/L at 25 °C
• application(s): USP Biologics; pharmaceutical (small molecule)
• format: neat

Descripción

General description

Citric acid is a weak organic acid naturally found in citrus fruits. It is widely used as an acidulant, preservative, and flavoring agent in the food and pharmaceutical industries.​ In pharmaceutical formulations, citric acid acts as a buffering agent to control pH and enhance the stability of active ingredients. The USP Citric Acid standard ensures the consistency and quality of citric acid used in these applications.The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics.

Application

Citric acid USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Anhydrous Citric Acid
• Citric Acid Monohydrate
• Magnesium Carbonate, Citric Acid, and Potassium Citrate for Oral Solution
• Monoglyceride Citrate
• Powdered Garcinia Hydroxycitrate Extract
• Anticoagulant Citrate Phosphate Dextrose Solution
• Potassium Citrate Extended-Release Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

This product is part of USP Biologics Program.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, has been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Información de seguridad

• pictograms: GHS07
• signalword: Warning
• hcodes: H319,H335
• pcodes: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Clase de almacenamiento: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable