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Delphine Meffre et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(24), 7587-7592 (2015-05-30)
The identification of new pathways governing myelination provides innovative avenues for remyelination. Liver X receptors (LXRs) α and β are nuclear receptors activated by oxysterols that originated from the oxidation of cholesterol. They are crucial for cholesterol homeostasis, a major
Madeleine Witting et al.
International journal of pharmaceutics, 486(1-2), 52-58 (2015-03-31)
Solid microneedles (MN) are a promising tool for dermal drug delivery. Particular focus lies on the field of vaccination due to pain-free, safe, hygienic and patient compliant antigen deposition. Diverse coating techniques and formulations have been developed to preserve vaccine
Lutz F Schweiger et al.
Anticancer research, 33(10), 4267-4270 (2013-10-15)
Malignant melanoma is a type of skin cancer which can spread rapidly if not detected early and left untreated. Positron Emission Tomography (PET) is a powerful imaging technique for detecting cancer but with only a limited number of radiotracers available
J Bewick et al.
Annals of the Royal College of Surgeons of England, 96(7), 526-529 (2014-09-24)
Methylene blue (MB) has been used in the identification of abnormal parathyroid glands in surgery for hyperparathyroidism. Its efficacy and safety profile have been questioned recently and this study sought to demonstrate such aspects in a unit where its use
Natássia Albuquerque Ribeiro et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 63(7), 569-580 (2014-03-19)
Marine algae are abundant sources of sulfated polysaccharides with various biological activities. Consequently, their biomolecules are of great of commercial interest. In this study, we investigated the potential antinociceptive activity of a sulfated polysaccharide obtained from the green seaweed Caulerpa
J How et al.
Gynecologic oncology, 137(3), 436-442 (2015-04-15)
With the debate over extent of lymphadenectomy in endometrial cancer, sentinel lymph node (SLN) mapping may provide a focused approach to evaluate the most relevant lymph nodes (LN) while minimizing the complications. We evaluated SLN mapping using filtered technetium(99), indocyanine
Nicolaas Lucius Gerlach et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(4), 666-671 (2014-02-01)
To establish the accuracy of cone-beam computed tomographic (CBCT) views in determining the position and diameter of the mandibular canal. Two freshly frozen cadaver heads, 1 dentate and 1 edentate, were used to acquire CBCT scans. Measurements on cross-sectional CBCT
CLEC9A modulates macrophage-mediated neutrophil recruitment in response to heat-killed Mycobacterium tuberculosis H37Ra
Cheng An-Chieh, et al.
Testing, 12(10), e0186780-e0186780 (2017)
Michelle A Nguyen et al.
ACS applied materials & interfaces, 7(24), 13238-13250 (2015-05-27)
We report a synthetic approach to form octahedral Cu2O microcrystals with a tunable edge length and demonstrate their use as catalysts for the photodegradation of aromatic organic compounds. In this particular study, the effects of the Cu(2+) and reductant concentrations
Thomas W Phillips et al.
Lab on a chip, 15(14), 2960-2967 (2015-06-10)
We report the use of a porous polytetrafluoroethylene capillary for the inline separation of liquid-liquid segmented flows, based on the selective wetting and permeation of the porous capillary walls by one of the liquids. Insertion of a narrow flow restriction
Nicolas Loire et al.
Environmental toxicology and chemistry, 32(10), 2396-2401 (2013-07-09)
Early-life-stage transgenic medaka are recognized as a pertinent model by the Organisation for Economic Co-operation and Development and are noncompliant with the European definition of a laboratory animal. However, autofluorescence confounds readout of fluorescent biomarkers. The authors determined the fluorescence
Hiroki Yoshimatsu et al.
American journal of physiology. Gastrointestinal and liver physiology, 306(2), G102-G110 (2013-11-23)
Riboflavin, also known as vitamin B2, is transported across the biological membrane into various organs by transport systems. Riboflavin transporter RFVT3 is expressed in the small intestine and has been suggested to localize in the apical membranes of the intestinal
Carlos Tarín et al.
Journal of the American Heart Association, 3(4), doi:10-doi:10 (2014-08-06)
Abdominal aortic aneurysm (AAA) involves leukocyte recruitment, inflammatory cytokine production, vascular cell apoptosis, neovascularization, and vascular remodeling, all of which contribute to aortic dilatation. Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) is a cytokine implicated in proinflammatory responses, angiogenesis
Bram Vivijs et al.
Applied and environmental microbiology, 80(19), 6054-6061 (2014-07-27)
Some members of the family Enterobacteriaceae ferment sugars via the mixed-acid fermentation pathway. This yields large amounts of acids, causing strong and sometimes even lethal acidification of the environment. Other family members employ the 2,3-butanediol fermentation pathway, which generates comparatively
Xiaohui Song et al.
Small (Weinheim an der Bergstrasse, Germany), 11(34), 4351-4365 (2015-06-13)
The origin of selectivity in the hollowing of silica nanoparticles is investigated to further understand silica. It is realized that, during the synthesis, the silica precursors are essentially ion-paired polyelectrolytes, whose nucleation depends on the concentration of the counter ions
Bedside methylene blue 'nephrostogram'.
S Pridgeon
Annals of the Royal College of Surgeons of England, 97(1), 83-83 (2014-12-19)
Green urine: what is the cause?
Venkata C Gourineni et al.
Connecticut medicine, 77(3), 191-191 (2013-04-18)
Ashok Aspatwar et al.
PloS one, 10(7), e0134263-e0134263 (2015-07-29)
Carbonic anhydrase related proteins (CARPs) X and XI are highly conserved across species and are predominantly expressed in neural tissues. The biological role of these proteins is still an enigma. Ray-finned fish have lost the CA11 gene, but instead possess
Ilya A Rodionov et al.
Soft matter, 11(24), 4921-4931 (2015-05-27)
Freeze-thaw processing of bovine serum albumin (BSA) aqueous solutions, which contain also the additives of denaturants (urea in this case) and thiol-bearing reductants [cysteine (Cys) in this case] leads to the formation of wide-pore cryogels. The properties and porous morphology
Gianluigi Li Bassi et al.
Chest, 147(5), 1327-1335 (2014-12-17)
Improvements in the design of the endotracheal tube (ETT) have been achieved in recent years. We evaluated tracheal injury associated with ETTs with novel high-volume low-pressure (HVLP) cuffs and subglottic secretions aspiration (SSA) and the effects on mucociliary clearance (MCC).
Sandra Thiemann et al.
The Journal of biological chemistry, 290(37), 22662-22677 (2015-07-29)
During inflammation, dendritic cells emigrate from inflamed tissue across the lymphatic endothelium into the lymphatic vasculature and travel to regional lymph nodes to initiate immune responses. However, the processes that regulate dendritic cell tissue egress and migration across the lymphatic
Erica di Martino et al.
Molecular cancer research : MCR, 13(1), 138-148 (2014-09-17)
Activating mutations of FGFR3 are a common and early event in bladder cancer. Ectopic expression of mutant FGFR3 in normal urothelial cells has both pro-proliferative and antiapoptotic effects at confluence, suggesting that mutant cells are insensitive to cell-cell contact inhibition.
Miriam Bolz et al.
PLoS neglected tropical diseases, 9(8), e0004011-e0004011 (2015-08-15)
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries. The majority of clinical presentations seen in patients are ulcers on
R Saravanan et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2235-2244 (2013-03-19)
Degradation of model organic dye and industry effluent was studied using different weight percentages of Ag into ZnO as a catalyst. In this study, the catalysts were prepared by thermal decomposition method, which was employed for the first time in
Q R J G Tummers et al.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 40(7), 850-858 (2014-05-28)
Despite recent developments in preoperative breast cancer imaging, intraoperative localization of tumor tissue can be challenging, resulting in tumor-positive resection margins during breast conserving surgery. Based on certain physicochemical similarities between Technetium((99m)Tc)-sestamibi (MIBI), an SPECT radiodiagnostic with a sensitivity of
D Martin-Gili et al.
Journal of materials science. Materials in medicine, 26(7), 211-211 (2015-07-16)
This study shows the potential risk of microfiltration between two different types of implant-abutment connections screwed at 45 Ncm: external and internal. For the first time the use of a mechanical artificial mouth is used with the values (compression and
Junming Hong et al.
Journal of nanoscience and nanotechnology, 14(4), 3247-3251 (2014-04-17)
The adsorption of methylene blue (MB) onto pore-expanded calcium fluoride sludge (ECF) by the batch adsorption technique was investigated. The results showed that the adsorption capacity increased with increasing MB concentration but decreased as pH was increased. In order to
Ashwati Raghunath
BMJ case reports, 2013, doi:10-doi:10 (2013-01-04)
The patient is a 52-year-old man with schizophrenia who developed severe, unremitting gingival pain after his ziprasidone dosage was increased from 80 to 120 mg. His physical examination and laboratory findings were unremarkable. He did not have any extra-pyramidal side
Derya Kocer et al.
Scandinavian journal of clinical and laboratory investigation, 74(5), 414-417 (2014-04-04)
The microscopic analysis of urine is essential for the diagnosis of patients with urinary tract infections. Quantitative urine culture is the 'gold standard' method for definitive diagnosis of urinary-tract infections, but it is labor-intensive, time consuming, and does not provide
Claus Hedegaard et al.
FEBS open bio, 3, 411-420 (2013-11-20)
Synapsin 1 (SYN1) is a phosphoprotein involved in nerve signal transmission. The porcine SYN1 promoter orthologue was cloned and characterized to provide a means of expressing a transgene specifically in neurons. The nucleotide sequence of the promoter displayed a high
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