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W J Chang et al.
Journal of biochemistry, 80(5), 975-981 (1976-11-01)
1. The Type B acid protease from Aspergillus niger var. macrosporus was inactivated by reaction with diazoacetyl-DL-norleucine methyl ester (DAN), DL-1-diazo-3-tosylamido-2-heptanone (DTH), and L-1-diazo-3-tosylamido-4-phenyl-2-butanone (DTPB) in the presence of cupric ions. The reaction with DAN took place with 1:1 stoichiometry.
Lucio Isa
Chimia, 67(4), 231-235 (2013-08-24)
Since the seminal work of Pickering and Ramsden more than a century ago, adsorption of solid micro- and nanoparticles at the interface between two fluids has been recognized as a means to enormously improve emulsion stability against coalescence. Despite their
Chang Soo Eun et al.
Helicobacter, 19(6), 407-416 (2014-07-24)
Helicobacter pylori (H. pylori) infection plays an important role in the early stage of cancer development. However, various bacteria that promote the synthesis of reactive oxygen and nitrogen species may be involved in the later stages. We aimed to determine
Rossella Melchiotti et al.
BMC medical genetics, 15, 73-73 (2014-06-28)
Extracellular ATP is a pro-inflammatory molecule released by damaged cells. Regulatory T cells (Treg) can suppress inflammation by hydrolysing this molecule via ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), also termed as CD39. Multiple studies have reported differences in CD39+ Treg percentages
[The cutting-edge of medicine; hyponatremia and water metabolism disorders in elderly].
San-e Ishikawa
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 102(7), 1807-1813 (2013-08-21)
Chunna Liu et al.
Pharmacological reports : PR, 67(2), 394-398 (2015-02-26)
Urocortin (UCN) is a newly identified vascular-active peptide that has been shown to reverse cardiovascular remodeling and improve left ventricular (LV) function. The effects and mechanism of urocortin 2 (UCN2) in vivo on the electrical remodeling of left ventricle and
Klaus Gerwert et al.
Biochimica et biophysica acta, 1837(5), 606-613 (2013-09-24)
Protein-bound internal water molecules are essential features of the structure and function of microbial rhodopsins. Besides structural stabilization, they act as proton conductors and even proton storage sites. Currently, the most understood model system exhibiting such features is bacteriorhodopsin (bR).
Kazuyuki Matsushita et al.
Oncotarget, 6(7), 5102-5117 (2015-02-12)
FUSE-binding protein (FBP)-interacting repressor (FIR) is a c-myc transcriptional suppressor. A splice variant of FIR that lacks exon 2 in the transcriptional repressor domain (FIRΔexon2) upregulates c-myc transcription by inactivating wild-type FIR. The ratio of FIRΔexon2/FIR mRNA was increased in
Rachel Parke-Houben et al.
Journal of materials science. Materials in medicine, 26(2), 107-107 (2015-02-11)
Three-dimensional scaffolds based on inverted colloidal crystals (ICCs) were fabricated from sequentially polymerized interpenetrating polymer network (IPN) hydrogels of poly(ethyleneglycol) and poly(acrylic acid). This high-strength, high-water-content IPN hydrogel may be suitable for use in an artificial cornea application. Development of
Wei Zhang-Sun et al.
FEBS letters, 589(1), 165-171 (2014-12-06)
The levels of sulfate-reducing bacteria (SRB), including Desulfovibrionaceae, in the gut increase following a fat-enriched diet. Endotoxins from gut microbiota contribute to the inflammation process, leading to metabolic diseases. Thus, we sought to characterize the lipid A structures of Desulfovibrionaceae
Shaoyin Wang et al.
Organic letters, 16(13), 3592-3595 (2014-06-25)
A novel Lewis acid catalyzed dehydrative [3 + 3]-annulation of readily available benzylic alcohols and propargylic alcohols was developed to give polysubstituted carbazoles and naphthalenes in moderate to good yields with water as the only byproduct. The reaction was presumed
M O Oke et al.
Pakistan journal of biological sciences : PJBS, 16(24), 2015-2020 (2014-02-13)
The nutritional and anti-nutritional compositions of African Yam Bean (AYB) and Lima bean flours under different processing methods were determined. Nutritional and anti-nutritional properties studied include moisture content, crude protein, crude fibre, ash content, ether extract, carbohydrate, tannin, protease inhibitor
Fanbin Meng et al.
International journal of oncology, 46(3), 1109-1120 (2014-12-17)
CCL18 is a chemokine that is primarily expressed in monocytes, macrophages and immature dendritic cells and plays a crucial role in immune and inflammation responses. Recently, CCL18 was found to play pivotal roles in the development of several kinds of
Hanne Haslene-Hox et al.
American journal of physiology. Heart and circulatory physiology, 308(1), H18-H28 (2014-11-09)
Elements of the extracellular matrix (ECM), notably collagen and glucosaminoglycans, will restrict part of the space available for soluble macromolecules simply because the molecules cannot occupy the same space. This phenomenon may influence macromolecular drug uptake. To study the influence
Anne-Coline Laurent et al.
Cardiovascular research, 105(1), 55-64 (2014-11-21)
Stimulation of β-adrenergic receptors (β-AR) increases cAMP production and contributes to the pathogenesis of cardiac hypertrophy and failure through poorly understood mechanisms. We previously demonstrated that Exchange protein directly activated by cAMP 1 (Epac1)-induced hypertrophy in primary cardiomyocytes. Among the
Bo-Ram Kim et al.
Tissue engineering. Part A, 20(23-24), 3279-3289 (2014-06-18)
To confirm the effect of recombinant human bone morphogenetic protein-2 (BMP-2) for bone regeneration, BMP-2-loaded polycaprolactone (PCL)-gelatin (Gel)-biphasic calcium phosphate (BCP) fibrous scaffolds were fabricated using the electrospinning method. The electrospinning process to incorporate BCP nanoparticles into the PCL-Gel scaffolds
Daniela Rigano et al.
Fitoterapia, 99, 198-203 (2014-10-07)
A new acetophenone derivative named gnaphaliol 9-O-propanoate (1) was isolated from the chloroform fraction of EtOH extract of Helichrysum italicum ssp. italicum flowers along with the five known acetophenones 12-acetoxytremetone (2), 13-(2-methylpropanoyloxy)toxol (3), [2,3-dihydro-2-[1-(hydroxymethyl)ethenyl]-5-benzofuranyl]-ethanone (4), 1-[2-[1-[(acetyloxy)methyl]ethenyl]-2,3-dihydro-3-hydroxy-5-benzofuranyl]-ethanone (5) and gnaphaliol (6).
Asya Akbar et al.
International journal of food microbiology, 188, 116-121 (2014-08-12)
Two new species of Aspergillus (A. aculeatinus, A. sclerotiicarbonarius) were previously isolated from coffee in Thailand. The objective of this study was to examine the effect of interacting environmental factors of water availability (water activity, aw) and temperature on lag
José Zorzin et al.
The journal of adhesive dentistry, 16(6), 541-546 (2014-12-18)
To evaluate the bonding performance of self-adhesive resin cements to zirconia and lithium disilicate in self- and dual-curing modes before and after thermocycling. Rectangular bars (3 mm high, 3 mm wide, 9 mm long) were manufactured from zirconia (Vita In-Ceram
Should water precautions be recommended for children with tympanostomy tubes?
Lyndy J Wilcox et al.
The Laryngoscope, 124(1), 10-11 (2013-12-07)
Yubin Zeng et al.
Journal of nanoscience and nanotechnology, 14(6), 4579-4583 (2014-04-18)
Uniform and assembled LaBO3 nanocrystals have been successfully synthesized via a facile hydrothermal method. These assemblies exhibit a rod-shape morphology and each of them consists of small LaBO3 nanocrystals which are tightly attached together. The phase, surface and morphology of
Buzhu Yu et al.
Phytochemistry, 108, 77-86 (2014-10-14)
The remodelling of membrane lipids contributes to the tolerance of plants to stresses, such as freezing and deprivation of phosphorus. However, whether and how this remodelling relates to tolerance of PEG-induced osmotic stress has seldom been reported. Thellungiella salsuginea is
Sebastien Trachsel et al.
Journal of applied physiology (Bethesda, Md. : 1985), 118(6), 768-775 (2015-01-01)
Inhaled nitric oxide (INO) improves ventilation-perfusion matching and alleviates pulmonary hypertension in patients with acute respiratory distress syndrome. However, outcome has not yet been shown to improve, and nonresponse is common. A better understanding of the mechanisms by which INO
Stephen Estes et al.
Developmental neurobiology, 75(5), 435-451 (2014-09-25)
The electrical activity in developing and mature neurons determines the intracellular calcium concentration ([Ca(2+)]i), which in turn is translated into biochemical activities through various signaling cascades. Electrical activity is under control of neuromodulators, which can alter neuronal responses to incoming
Bjoern Traenkle et al.
Molecular & cellular proteomics : MCP, 14(3), 707-723 (2015-01-18)
β-catenin is the key component of the canonical Wnt pathway and plays a crucial role in a multitude of developmental and homeostatic processes. The different tasks of β-catenin are orchestrated by its subcellular localization and participation in multiprotein complexes. To
Josep Anton Mir-Tutusaus et al.
The Science of the total environment, 500-501, 235-242 (2014-09-15)
Use of agrochemicals is a worldwide practice that exerts an important effect on the environment; therefore the search of approaches for the elimination of such pollutants should be encouraged. The degradation of the insecticides imiprothrin (IP) and cypermethrin (CP), the
Mohammed Auwal Ibrahim et al.
Acta poloniae pharmaceutica, 70(4), 709-719 (2013-08-08)
The present study was conducted to investigate the anti-oxidative activities of different solvent extracts of Cassia singueana parts. Our results indicate that all the extracts have reducing power (Fe3+ --> Fe2+) and DPPH radical scavenging abilities. However, the ethyl acetate
Chieh-Jui Tsou et al.
Nanoscale, 7(9), 4217-4225 (2015-02-13)
Continuous and simultaneous 3D single-particle movement and local pH detection in HeLa cells were demonstrated for the first time by combining fluorescent mesoporous silica nanoparticles (FMSNs) and a single-particle tracking (SPT) technique with a precision of ∼10 nm. FMSNs, synthesized
Sarah Kittel-Schneider et al.
Journal of psychopharmacology (Oxford, England), 29(1), 31-38 (2014-10-17)
Several studies have shown altered levels of nitric oxide (NO) and its stable metabolites (NOx (-)) in blood and cerebrospinal fluid of psychiatric patients. The aim of our study was to replicate previous findings and investigate the influence of the
Yanliang Tan et al.
Health physics, 107(3), 255-260 (2014-07-30)
Generally, 88% of the freshly generated 218Po ions decayed from 222Rn are positively charged. These positive ions become neutralized by recombination with negative ions, and the main source of the negative ions is the OH- ions formed by radiolysis of
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