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493546
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Palabra clave:'493546'
Mostrando 1-30 of 3589 resultados para "493546" en el plazo de Papeles
Wen-Ying Zhang et al.
World journal of gastroenterology, 19(22), 3397-3403 (2013-06-27)
Endoscopic ultrasonography (EUS) has evolved into a useful therapeutic tool for treating a broad range of tumors since being introduced into clinical practice as a diagnostic modality nearly three decades ago. In particular, EUS-guided fine-needle injection has proven a successful
Golo M J Meyer et al.
Analytical and bioanalytical chemistry, 407(3), 761-778 (2014-09-23)
Mesembrine and mesembrenone are the main alkaloids of Sceletium tortuosum, a plant species that was used for sedation and analgesia by the KhoiSan, previously known as Hottentots, a tribe in South Africa. After fermentation, the obtained preparation called "Kanna" or
Stefano Scaramuzza et al.
Physical chemistry chemical physics : PCCP, 17(42), 28076-28087 (2015-03-10)
Alloy nanoparticles are characterized by the combination of multiple interesting properties, which are attractive for technological and scientific purposes. A frontier topic of this field is nanoalloys with compositions not thermodynamically allowed at ordinary temperature and pressure (i.e. metastable), because
K L Schully et al.
International journal of pharmaceutics, 495(2), 849-861 (2015-10-03)
Melioidosis, a potentially lethal disease of humans and animals, is caused by the soil-dwelling bacterium Burkholderia pseudomallei. Due to B. pseudomallei's classification as a Tier 1 Select Agent, there is substantial interest in the development of an effective vaccine. Yet
Serena Deiana et al.
Behavioural pharmacology, 26(8 Spec No), 748-765 (2015-08-20)
Deficiencies in social activities are hallmarks of numerous brain disorders. With respect to schizophrenia, social withdrawal belongs to the category of negative symptoms and is associated with deficits in the cognitive domain. Here, we used the N-methyl-D-aspartate receptor antagonist dizocilpine
Ingrid R Cordeiro et al.
Biology open, 4(9), 1180-1193 (2015-09-01)
Human adipose-derived stromal cells (hADSC) are a heterogeneous cell population that contains adult multipotent stem cells. Although it is well established that hADSC have skeletal potential in vivo in adult organisms, in vitro assays suggest further differentiation capacity, such as
Ra Ham Lee et al.
Oncology reports, 33(2), 631-638 (2014-12-02)
7,8-Dihydroxyflavone (7,8-DHF) is a member of the flavonoid family and has recently been identified as a brain-derived neurotrophic factor mimetic that selectively activates tropomyosin-receptor kinase B with high affinity. The antioxidant and anticancer effects of 7,8-DHF have been reported. However
Vendula Studentova et al.
Folia microbiologica, 60(2), 119-129 (2014-09-30)
Carbapenemase-mediated resistance to carbapenems in Enterobacteriaceae has become the main challenge in the treatment and prevention of infections recently. The partially unnoticed spread of OXA-48-type carbapenemase producers is usually assigned to low minimum inhibitory concentrations (MICs) of carbapenems that OXA-48-producing
Florian Mertes et al.
BMC genomics, 16, 925-925 (2015-11-14)
Next Generation Sequencing has proven to be an exceptionally powerful tool in the field of genomics and transcriptomics. With recent development it is nowadays possible to analyze ultra-low input sample material down to single cells. Nevertheless, investigating such sample material
Nidhi Nath et al.
Journal of immunological methods, 426, 95-103 (2015-09-01)
Antibodies labeled with small molecules such as fluorophore, biotin or drugs play an important role in various areas of biological research, drug discovery and diagnostics. However, the majority of current methods for labeling antibodies is solution-based and has several limitations
Zhe-Yi Hu et al.
Clinical pharmacokinetics, 53(9), 825-836 (2014-08-12)
Human carboxylesterase-1 (CES1) is an enzyme that is primarily expressed in the liver, where it plays an important role in the metabolism of many commonly used medications. Ethanol (alcohol)-mediated inhibition of CES1 and loss-of-function polymorphisms in the CES1 gene can
Hao Ding et al.
Digestive diseases and sciences, 60(2), 375-381 (2014-10-09)
Previous studies have revealed significantly increased levels of plasma and mucosal homocysteine (Hcy) in patients with Crohn's disease (CD); however, whether Hcy is involved in intestinal fibrosis of CD remains unclear. This study aimed to investigate the effects of Hcy
Elizabeth A Mueller et al.
PloS one, 10(3), e0120280-e0120280 (2015-03-24)
Skin and surgical infections due to Staphylococcus aureus, Pseudomonas aeruginosa, and Acinetobacter baumannii are causes of patient morbidity and increased healthcare costs. These organisms grow planktonically and as biofilms, and many strains exhibit antibiotic resistance. This study examines the antibacterial
Ran Du et al.
PloS one, 9(4), e94480-e94480 (2014-04-17)
The rising demand for bioethanol, the most common alternative to petroleum-derived fuel used worldwide, has encouraged a feedstock shift to non-food crops to reduce the competition for resources between food and energy production. Sweet sorghum has become one of the
G P Lv et al.
Journal of pharmaceutical and biomedical analysis, 109, 105-111 (2015-03-15)
It was shown that different extracts had significant differences in the toxicity of Polygonum multiflorum. In this study, the effect of sample preparation on components and liver toxicity of different extracts from P. multiflorum were determined. Hepatoxic components were discovered
Iu A Vinnik et al.
Klinichna khirurhiia, (12)(12), 10-14 (2014-02-08)
Efficacy of a new method of intraoperative regional sympathetic blockade of splanchnic nerves was estimated, basing on the results of surgical treatment of 3134 patients, suffering gastric cancer. While comparing the immediate results of surgical interventions there was established, that
Shawna A Shirley et al.
Current gene therapy, 15(1), 32-43 (2014-11-22)
Effective delivery still remains a major hurdle in the development of gene based therapies. While technological advances have occurred that have improved delivery in general, there is still a need for controlled delivery in order to achieve therapeutic effects. Gene
Dimitrios K Filippiadis et al.
La Radiologia medica, 119(7), 462-469 (2014-06-05)
Benign tumors and metastatic bone lesions can be treated by ablation techniques performed either alone or in combination with other percutaneous techniques. Ablation techniques include ethanol or acetic acid injection and thermal ablation by means of energy deposition [including laser
Tomáš Taubner et al.
International journal of biological macromolecules, 72, 11-18 (2014-08-12)
Carboxymethylcellulose (CMC) was selected as substrate for amidation based on previous results described for monocarboxy cellulose (MCC) with the aim to prepare highly substituted products. In comparison with MCC containing uronic carboxyl groups at C-6 position, O-carboxymethyl groups in CMC
Yong Xia et al.
Cancer letters, 355(2), 297-309 (2014-10-11)
Benzothiazole derivatives have received considerable attentions for their potencies in cancer therapy. In the present study, we reported that SKLB316, a novel synthesized benzothiazole derivative, exhibits activities to inhibit colorectal and pancreatic cancer in vitro and in vivo by inducing
Yang Yang et al.
Oncotarget, 5(23), 11886-11896 (2014-11-02)
Higher rate of glycolysis has been long observed in cancer cells, as a vital enzyme in glycolysis, lactate dehydrogenase A (LDH-A) has been shown with great potential as an anti-cancer target. Accumulating evidence indicates that inhibition of LDH-A induces apoptosis
Matthew Hennig et al.
The Journal of surgical research, 154(2), 187-195 (2009-03-27)
Chronic ethanol intake is a significant risk factor for the development of cirrhosis and hepatocellular carcinoma (HCC). The effects of ethanol on extracellular signal-regulated kinase (ERK) activation, transforming growth factor alpha (TGF-alpha), and HCC growth were examined in this study.
Erin M Rock et al.
Psychopharmacology, 231(16), 3207-3215 (2014-03-07)
The effectiveness of cannabidiolic acid (CBDA) was compared with other potential treatments for anticipatory nausea (AN), using a rat model of contextually elicited conditioned gaping reactions. The potential of ondansetron (OND), Δ(9)-tetrahydrocannabinol (THC), chlordiazepoxide (CDP), CBDA, and co-administration of CBDA
Philip James Thomas Reardon et al.
Journal of biomedical materials research. Part A, 103(12), 3781-3789 (2015-05-28)
Calcium phosphate nanomaterials with controllable morphology and mesostructure were synthesized via a rapid and energy efficient microwave method. An increase in aspect ratio from nanoplates to nanorods was achieved by increasing the solvent chain length, accompanied by a subsequent about
Qizhong Fu et al.
International journal of molecular medicine, 36(5), 1417-1425 (2015-12-10)
Skeletal metastasis is the major problem in the management of prostate cancer (PCa). Even though the regulatory role of microRNAs (miRNAs) in the control of tumor metastases has been well described in numerous types of cancer, the importance in bone
Seungki Lee et al.
Scientific reports, 5, 16045-16045 (2015-11-03)
Long-term preservation of fish fertility is essential for the conservation of endangered fishes. However, cryopreservation techniques for fish oocytes and embryos have not yet been developed. In the present study, functional eggs and sperm were derived from whole rainbow trout
K Sanjana P Devi et al.
International immunopharmacology, 25(1), 207-217 (2015-02-11)
With the increase in cancer progression, alternatives in the medicinal field with minimal side effects need to be ascertained. In this context, for the first time novel glucans/glycans isolated from the mycelia and fruit body of Pleurotus ostreatus have been
S Bascil et al.
Bratislavske lekarske listy, 115(9), 588-592 (2014-10-17)
Acromegaly is a complex syndrome which influences the connective tissue and bone metabolism. Although the effects of excess growth hormone on bone tissue are well known, its effect on periodontal tissue is an enigma. A total of 23 acromegalic patients
Ignacio Gonzalez Segura et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 44(3), 178-184 (2014-07-30)
Prevention and early diagnosis have the greatest potential for public health and are the most effective method in the long-term to control oral cancer. The aim was to apply PAP staining together with AgNOR staining and morphometric analysis in oral
Claire Acevedo et al.
Bone, 81, 352-363 (2015-08-09)
Bisphosphonates are widely used to treat osteoporosis, but have been associated with atypical femoral fractures (AFFs) in the long term, which raises a critical health problem for the aging population. Several clinical studies have suggested that the occurrence of AFFs
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