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A Vyskocil et al.
Human & experimental toxicology, 27(6), 471-476 (2008-09-12)
The ability of chemicals to produce hearing loss themselves or to promote noise-induced hearing loss has been reported for some organic solvents. The objective of this study was to review the literature on the effects of low-level exposure to n-hexane
Cheruvu Hanumanth Srikanth et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 960, 82-86 (2014-05-06)
The aim of the present study was to investigate the distribution of clofazimine (CLF) in rat bone marrow cells by a validated reverse phase high performance liquid chromatography. CLF and chlorzoxazone (I.S) were extracted by liquid-liquid extraction from plasma and
Katharina Röttger et al.
The journal of physical chemistry. A, 117(12), 2469-2478 (2013-03-21)
Guanosine (G) derivatives in nonpolar aprotic solvents self-assemble to intricate hydrogen-bonded supramolecular architectures, including dimers, ribbons, and cyclic quartets. Considerable interest exists in the nature of the excited electronic states, their lifetimes and the radiationless deactivation mechanisms of the molecules
S D Dowall et al.
Journal of immunology research, 2015, 347903-347903 (2015-03-31)
Ebola virus is responsible for causing severe hemorrhagic fevers, with case fatality rates of up to 90%. Currently, no antiviral or vaccine is licensed against Ebola virus. A phosphatidylserine-targeting antibody (PGN401, bavituximab) has previously been shown to have broad-spectrum antiviral
Maki Kanda et al.
Journal of AOAC International, 98(1), 230-247 (2015-04-11)
Residues of 37 polar veterinary drugs belonging to six families (quinolones, tetracyclines, macrolides, lincosamides, sulfonamides, and others) in livestock and fishery products were determined using a validated LC-MS/MS method. There were two key points in sample preparation. First, extraction was
Ilona Olędzka et al.
Journal of pharmaceutical and biomedical analysis, 102, 45-53 (2014-09-23)
The purpose of this work is the evaluation of the nutritional status of patients with cystic fibrosis (CF), based on the level of vitamin C in urine and vitamins A and E in serum, using the fast, selective and fully
Wei-Wei Zhao et al.
Journal of chromatography. A, 1370, 121-128 (2014-12-03)
Metal-organic frameworks (MOFs) have great potential for applications in chromatography due to their highly tailorable porous structures and unique properties. In this work, the stable MOF UiO-66 was evaluated as both a normal-phase (NP-) and a reverse-phase (RP-) stationary phase
Panfeng Yu et al.
Journal of chromatography. A, 1348, 27-33 (2014-05-20)
In this paper, polyethylene glycol modified (PEGylated) magnetic carbon nanotubes were developed as solid-phase extraction nanosorbents for the determination of methylprednisolone in rat plasma. The procedure mainly involved two steps including preparation of PEGylated magnetic nanosorbents and bioanalysis. Monodisperse magnetites
Kohji Abe et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 34(12), 1907-1913 (2014-09-18)
To assess reactive oxygen species (ROS) production by detecting the fluorescent oxidation product, hydroethidine has been used extensively. The present study was undertaken to evaluate the potential of the hydroethidine derivative as a radiotracer to measure in vivo brain ROS
Marta Palusinska-Szysz et al.
International journal of molecular sciences, 15(5), 8256-8279 (2014-05-14)
Phosphatidycholine (PC) is the major membrane-forming phospholipid in eukaryotes but it has been found in only a limited number of prokaryotes. Bacteria synthesize PC via the phospholipid N-methylation pathway (Pmt) or via the phosphatidylcholine synthase pathway (Pcs) or both. Here
Ottmar Golf et al.
Journal of the American Society for Mass Spectrometry, 26(1), 44-54 (2014-11-09)
Here we present a proof of concept cross-platform normalization approach to convert raw mass spectra acquired by distinct desorption ionization methods and/or instrumental setups to cross-platform normalized analyte profiles. The initial step of the workflow is database driven peak annotation
Maria Celeiro et al.
Journal of chromatography. A, 1344, 1-14 (2014-04-29)
An effective, simple and low cost sample preparation method based on matrix solid-phase dispersion (MSPD) followed by gas chromatography-mass spectrometry (GC-MS) or gas chromatography-triple quadrupole-mass spectrometry (GC-MS/MS) has been developed for the rapid simultaneous determination of 38 cosmetic ingredients, 25
Bin Xu et al.
Talanta, 132, 245-251 (2014-12-06)
A new isotope-dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for determination of sulfur mustard (SM) has been developed using a direct chemical derivatization method by nucleophile potassium thioacetate (PTA) in aqueous solution. The reaction conditions for derivatization, such as reaction
Cécile Arellano et al.
Journal of pharmaceutical and biomedical analysis, 100, 254-261 (2014-09-01)
A selective and accurate analytical method is needed to quantify tamoxifen and its phase I metabolites in a prospective clinical protocol, for evaluation of pharmacokinetic parameters of tamoxifen and its metabolites in adjuvant treatment of breast cancer. The selectivity of
B S Marpoe et al.
Journal of occupational and environmental hygiene, 9(10), 572-579 (2012-08-29)
A study was conducted to examine whether there are significant differences between organic vapor concentrations measured using charcoal tubes with three different configurations: uncovered sample holder (open tube), SKC, and Buck brand covered sample holders. A fractional factorial experimental design
Rattikorn Intarakumhaeng et al.
International journal of pharmaceutics, 476(1-2), 266-276 (2014-09-28)
Understanding the effects of solvents upon percutaneous absorption can improve drug delivery across skin and allow better risk assessment of toxic compound exposure. The objective of the present study was to examine the effects of solvents upon the deposition of
Xiaolan Zhang et al.
International journal of hygiene and environmental health, 218(1), 99-106 (2014-09-27)
Although early exposure to environmental pollutants may have important toxicological consequences, the mechanisms of transplacental transfer of synthetic musks are still not well understood. The objective of the present study was to learn the musk contaminations in three matrices, including
Renato Almeida Sarmento et al.
Ecology letters, 14(3), 229-236 (2011-02-09)
Phytopathogens and herbivores induce plant defences. Whereas there is evidence that some pathogens suppress these defences by interfering with signalling pathways involved in the defence, such evidence is scarce for herbivores. We found that the invasive spider mite Tetranychus evansi
Zheyuan Qian et al.
Journal of pharmaceutical and biomedical analysis, 102, 299-304 (2014-12-03)
A highly sensitive and selective liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and fully validated for quantification of arotinolol enantiomers in rat plasma using haloperidol as the internal standard. After solid phase extraction of 50.0 μL rat plasma in
Matthew J Farrar et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 35(4), 667-675 (2015-01-08)
The availability of transgenic strains has made the laboratory mouse a popular model for the study of healthy and diseased state spinal cord (SC). Essential to identifying physiologic and pathologic events is an understanding of the microvascular network and flow
Thermodynamic properties of n-hexane.
Grigoryev BA, et al.
International Journal of Thermophysics, 9(3), 439-452 (1988)
David A Alvarez et al.
Marine pollution bulletin, 81(2), 347-354 (2013-05-21)
Three passive sampling devices (PSDs), polar organic chemical integrative samplers (POCIS), polyethylene devices (PEDs), and solid-phase microextraction (SPME) samplers were used to sample a diverse set of chemicals in the coastal waters of San Francisco Bay and the Southern California
Garret Munch et al.
Bioresource technology, 185, 49-55 (2015-03-10)
The growth, lipid production, and carbon use efficiency of two oleaginous yeasts, Rhodosporidium babjevae and Rhodosporidium diobovatum, were compared under nitrogen-limiting conditions with glycerol as the carbon source. Final biomass concentrations of R. babjevae and R. diobovatum were 9.4±0.80g/L and
Gyuyeon Choi et al.
The Science of the total environment, 491-492, 219-226 (2014-03-19)
Polybrominated diphenyl ethers (PBDEs) are of growing public health concern because of their potential toxicities which range from endocrine disruption to neurodevelopment. However, information on their exposure among sensitive human populations is limited. The objectives of this study were to
Zhi Guo et al.
Bioresource technology, 186, 238-245 (2015-03-31)
A study on the optimization of CO2 usage during outdoor microalgae cultivation in order to further maximize the CO2 to biomass conversion efficiency is presented. A constant supply of CO2 was found to be non-essential for culturing microalgae outdoors in
Melissa Salmon et al.
Nature communications, 6, 6143-6143 (2015-02-04)
The emergence of terpene cyclization was critical to the evolutionary expansion of chemical diversity yet remains unexplored. Here we report the first discovery of an epistatic network of residues that controls the onset of terpene cyclization in Artemisia annua. We
The thermal decomposition of n-hexane.
Ebert KH, et al.
International Journal of Chemical Kinetics, 15(5), 475-502 (1983)
Subhasree Nag et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 969, 235-240 (2014-09-10)
In the present study, a specific and sensitive liquid chromatography-triple quadrupole mass spectrometry method was developed and validated for the determination of SP-141, a novel pyrido[b]indole anticancer agent. After a liquid-liquid extraction with n-hexane-dichloromethane-2-propanol (20:10:1, v/v/v) mixture, the analyte was
Hyun-Kyung Lee et al.
Ecotoxicology and environmental safety, 115, 195-202 (2015-02-24)
Data on persistent organochlorines (OCs) in sharks are scarce. Concentrations of OCs such as polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) were determined in the muscle tissue of 13 shark species (n=105) collected from offshore (Indian and Pacific Oceans) and
Anthony Puntel et al.
Biomaterials, 44, 103-110 (2015-01-27)
Retinal degeneration impairs the vision of millions in all age groups worldwide. Increasing evidence suggests that the etiology of many retinal degenerative diseases is associated with impairment in biochemical reactions involved in the visual cycle, a metabolic pathway responsible for
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