Search Within
Applied Filters:
Palabra clave:'650560'
Showing 1-30 of 138 resultados for "

650560

" within Papeles
Emily E Woodward et al.
Journal of environmental quality, 43(6), 1933-1941 (2015-01-21)
The increase in endocrine-disrupting compounds in the environment has generated research focused on the behavior of these compounds in natural soil and water ecosystems. To understand how estrogens behave in the soil environment as a result of 25+ yr of...
Rikako Takahiro et al.
Biological & pharmaceutical bulletin, 38(1), 58-65 (2015-03-07)
The aim of this study was to characterize the kinetics of metabolite formation of the phosphodiesterase type-5 (PDE5) inhibitors sildenafil and tadalafil by CYP3A4, CYP3A5, and CYP3A7 isoforms. The formations of N-desmethyl sildenafil and desmethylene tadalafil were examined using CYP3A...
Julie A Ray et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 970, 102-107 (2014-09-24)
Accurate measurement of aldosterone is important for the standardized testing of primary hyperaldosteronism. Commercial immunoassays show substantial between-method variations resulting in significant clinical consequences. We developed a specific two dimensional (2D)-LC-MS/MS method for measuring aldosterone in human serum and plasma...
Topical dissolution treatment of cholesterol gallstones with methyl tert-butyl ether.
J L Thistle
Seminars in liver disease, 10(3), 187-190 (1990-08-01)
Yuru Wang et al.
Environmental science & technology, 48(24), 14534-14542 (2014-11-26)
A sulfate radical-based advanced oxidation process (SR-AOP) has received increasing application interest for the removal of water/wastewater contaminants. However, limited knowledge is available on its side effects. This study investigated the side effects in terms of the production of total...
Scott Phillips et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 4(2), 115-126 (2008-06-24)
This paper reviews the published information assessing the kinetics and potential for adverse health effects related to exposure to the fuel oxygenate, methyl tert-butyl ether (MTBE). Data were obtained from previously published reports, using human data where possible. If human...
Laura J Owen et al.
Annals of clinical biochemistry, 50(Pt 5), 489-491 (2013-07-31)
Supported liquid extraction (SLE) techniques are relatively new compared to other sample preparation approaches such as solid phase extraction (SPE), liquid-liquid extraction (LLE) and protein precipitation (PPE). We investigated the use of SLE as an alternative to SPE for the...
Enrico Gerace et al.
Forensic science international, 243, 68-73 (2014-05-23)
The distribution of mephedrone in the body fluids and tissues of a subject found dead after the concomitant intake of cocaine and mephedrone is reported. Mephedrone (4-methylmethcathinone) is a designer drug of the phenethylamine family that is able to cause...
Lipid extraction by methyl-tert-butyl ether for high-throughput lipidomics.
Matyash V, et al.
Journal of Lipid Research, 49(5), 1137-1146 (2008)
Sarah K Abbott et al.
Lipids, 48(3), 307-318 (2013-01-29)
We have developed a protocol suitable for high-throughput lipidomic analysis of human brain samples. The traditional Folch extraction (using chloroform and glass-glass homogenization) was compared to a high-throughput method combining methyl-tert-butyl ether (MTBE) extraction with mechanical homogenization utilizing ceramic beads....
Susan M Christner et al.
Journal of pharmaceutical and biomedical analysis, 100, 199-204 (2014-08-30)
Epothilones are relatively new tubulin-poison anticancer drugs. Iso-fludelone (KOS-1803) is a synthetic third generation epothilone drug discovered at Memorial Sloan Kettering Cancer Center, and currently in phase I clinical trials. We report an LC-MS/MS assay for the sensitive, accurate and...
Da-Hye Kim et al.
Environmental pollution (Barking, Essex : 1987), 192, 171-178 (2014-06-24)
Serum and urine samples from 120 children aged 5-13 years from Dae-gu, Korea, were analyzed for 16 perfluorinated compounds (PFCs). The total PFC concentrations in the serum were 4.26-29.70 ng/mL, and perfluorohexanesulfonate (PFHxS), perfluorooctanoic acid (PFOA), perfluorooctanesulfonate (PFOS, which was dominant...
Mohammad Ghasemian et al.
Environmental technology, 33(16-18), 1937-1943 (2012-12-18)
A laboratory-scale anaerobic sequencing batch reactor was used to evaluate treatment of a synthetic substrate mixture representing petrochemical wastewater containing methyl tert-butyl ether (MTBE), ethanol and acetic acid. Influent MTBE concentrations were 5, 10 and 50 mg/l (corresponding to MTBE...
João Cleverson Gasparetto et al.
PloS one, 10(3), e0118922-e0118922 (2015-03-11)
For decades guaco species have been empirically used for the treatment of respiratory diseases. However, studies have shown that the toxic and therapeutic effects of the main guaco metabolites are dose-dependent, and none clinical study was done to evaluate the...
Liangpo Liu et al.
Journal of separation science, 38(2), 247-253 (2014-11-12)
In this study, a novel method for the analysis of perfluorinated compounds in whole blood has been developed and validated. The method was developed by using a conventional reversed-phase C18 column as a trapping column for the elimination of background...
J-F Li et al.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 33(10), 1725-1732 (2014-05-09)
Hepatic steatosis affects disease progression in patients with chronic hepatitis C virus (HCV) infection. We investigated the plasma sphingolipid profile in patients with chronic hepatitis C (CHC) and whether there was an association between HCV-related steatosis and plasma sphingolipids. We...
Nan Yang et al.
Molecules (Basel, Switzerland), 20(3), 4319-4336 (2015-03-11)
A high-throughput, sensitive and specific LC-ESI-MS/MS method was established for the quantitative determination of GP205, a potent inhibitor of hepatitis C virus NS3/4A protease, in rat. The analyte was isolated from 25 μL plasma sample by 96-well LLE. Good linearity...
I Werner et al.
Environmental pollution (Barking, Essex : 1987), 111(1), 83-88 (2001-02-24)
Increased input of the fuel oxygenate methyl-tert-butyl ether (MTBE) into aquatic systems has led to concerns about its effect(s) on aquatic life. As part of a study conducted by University of California scientists for the State of California, the Aquatic...
J J Clary
Risk analysis : an official publication of the Society for Risk Analysis, 17(6), 661-672 (1998-02-17)
In male F344 rats exposed in a chronic inhalation study to methyl tertiary butyl ether (MTBE) a treatment related increase in severity of chronic nephropathy and mortality and an increase in hyaline droplets in the kidney were noted. Liver weights...
Sylvain Merel et al.
Chemosphere, 127, 238-245 (2015-03-10)
N,N-diethyl-m-toluamide (DEET), the active component of many insect repellents, is among the most frequently detected compounds in aqueous environments with concentrations reported in the ng L(-1) to μg L(-1) range. However, DEET is often detected in blanks and reported concentrations...
Ceinwen A Schreiner et al.
Regulatory toxicology and pharmacology : RTP, 70(2 Suppl), S29-S34 (2014-05-24)
Micronucleus and sister chromatid exchange (SCE) tests were performed for vapor condensate of baseline gasoline (BGVC), or gasoline with oxygenates, methyl tert-butyl ether (G/MTBE), ethyl tert butyl ether (G/ETBE), t-amyl methyl ether (G/TAME), diisopropyl ether (G/DIPE), t-butyl alcohol (TBA), or...
I Zabaleta et al.
Journal of chromatography. A, 1387, 13-23 (2015-02-25)
An analytical method for the simultaneous determination in fish liver and muscle tissue and mussel samples of 14 perfluorinated compounds (PFCs), including three perfluoroalkylsulfonates (PFSAs), seven perfluorocarboxylic acids (PFCAs), three perfluorophosphonic acids (PFPAs) and perfluorooctanesulfonamide (PFOSA), and 10 potential precursors...
Damayanthi Devineni et al.
Clinical therapeutics, 37(3), 610-628 (2015-02-11)
Canagliflozin is a sodium-glucose cotransporter 2 inhibitor approved for the treatment of type 2 diabetes mellitus (T2DM). Because T2DM is often associated with renal or hepatic impairment, understanding the effects of these comorbid conditions on the pharmacokinetics of canagliflozin, and...
Jérôme Cotton et al.
Journal of agricultural and food chemistry, 62(46), 11335-11345 (2014-10-31)
Analytical methods for food control are mainly focused on restricted lists of well-known contaminants. This paper shows that liquid chromatography-high-resolution mass spectrometry (LC/ESI-HRMS) associated with the data mining tools developed for metabolomics can address this issue by enabling (i) targeted...
Ping Du et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 967, 28-35 (2014-07-27)
Docetaxel lipid microsphere (DT-LM) is a novel formulation of docetaxel without Tween-80. A sensitive, robust and reproducible ultrafiltration (UF) followed by UPLC-MS/MS method was developed and validated for the quantification of unbound docetaxel in human plasma using paclitaxel as IS....
New approach of catalyst-free biodiesel production from canola oil in supercritical tert-butyl methyl ether (MTBE).
Farobie O, et al.
Fuel: The Science and Technology of Fuel and Energy, 135, 172-181 (2014)
Surajit Rakshit et al.
Langmuir : the ACS journal of surfaces and colloids, 29(6), 1808-1817 (2013-01-15)
The effect of hydrophobic interaction on water is still controversial and requires more detailed experimental and theoretical investigation. The interaction between organic-water molecular complexes might be indicative of the perturbation of hydrogen-bond network in the tetrahedral structure of bulk waters...
J Scott Boone et al.
Journal of chromatography. A, 1345, 68-77 (2014-05-06)
A trace analytical method was developed for the determination of seventeen specific perfluorinated chemicals (PFCs) in environmental and drinking waters. The objectives were to optimize an isotope-dilution method to increase the precision and accuracy of the analysis of the PFCs...
É V Trifonova et al.
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (4)(4), 16-20 (2013-02-14)
In article the data on interrelation between gallbladder contractility and a level of hormones of a thyroid gland (threeiodethyronine, thyroxine, thyrotropin hormone (TTH) and antibodies to thyreoperoxidase (AT to TPO)) in plasma of blood at 470 healthy persons and 540...
Y G Zhao et al.
Marine pollution bulletin, 83(1), 148-154 (2014-04-30)
Surface sediment and biota were collected from 12 sampling sites - seven along the Pearl River Delta and five along the Hong Kong coastline. Perfluorinated compound (PFC) concentrations were detected using a high-performance-liquid-chromatogram-tandem-mass-spectrometry system. Analytical results indicated that the total...
Página 1 de 5
Página 1 de 5