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Optimización para el análisis de alto rendimiento de cannabinoides en diversas matrices utilizando la columna Ascentis® Express C18
Una completa secuencia de trabajo para la separación mediante HPLC de 17 cannabinoides en diferentes productos del cannabis utilizando la columna Ascentis® Express C18 en un tiempo de ejecución más corto con estabilidad de los tiempos de retención. Más información
Supel™-Select Polymeric SPE
Supel-Select HLB SPE - a hydrophilic modified styrene based polymer developed for the solid phase extraction of a broad range of compounds from aqueous samples.
Ascentis® Express C8 U/HPLC Columns
When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.
HPLC Separation of Fluorinated Pharmaceutical Compounds on Supelco Ascentis Columns
Fluorinated compounds possess distinct characteristics that confer desirable physico-chemical properties compared to their non-fl uorinated analogs. Their abundance in pharmaceuticals, chemicals, consumer products and as environmental pollutants dictates the need for a reliable analytical method. Ascentis HPLC columns, by virtue
Isolation and LC-MS Characterization of Illicit Bath Salts in Urine
The combination of ion-exchange SPE with the HILIC HPLC separation provides a novel approach for the testing of problematic bath salt compounds.
Determination of L- and D-Lactic Acid Enantiomers by HPLC-MS-MS
Determination of L- and D-Lactic Acid Enantiomers by HPLC-MS-MS
Vitamin D epi-Metabolites Separated with HybridSPE-Phospholipid
This Sigma-Aldrich article continues to detail new methodology for the analysis of Vitamin D metabolites using HybridSPE-Phospholipid technology.
Investigating Matrix Interference in Analysis of Antiarrhythmic Cardiac Drugs in Plasma
For efficient therapeutic drug monitoring, it is important for clinicians to have access to fast and robust analytical methods for accurate assessment of drug efficacy. Industrial trends toward highly specific LC/MS applications over traditional immunoassay have resulted in the need
Improving the Chromatographic Separation of DMB-Labeled Sialic Acids for the Comparison of Biosimilars to Reference Materials
A significantly improved HPLC-fluorescence method for DMB-NANA and -NGNA, and application of this method to compare 2 candidate biosimilar therapeutic proteins to their respective RMs.
HPLC Analysis of Flavonoids on Ascentis® RP-Amide
Coumaric acid; Quercitrin; Myricetin; Quercetin
Improving HILIC Mode Chromatography by Choosing the Proper Injection and Wash Solvent
Improving HILIC Mode Chromatography by Choosing the Proper Injection and Wash Solvent
Method Optimization for LC-MS Analysis of Vitamin D Metabolite Critical Pairs in Serum
Novel sample prep technique coupled with the unique selectivity of the Ascentis Express F5 column enables a fast and simplified bioanalytical method for associated vitamin D metabolites.
LC/MS/MS Method for Determination of Glyphosate, AMPA, and Glufosinate in Cereals
Glyphosate and related compounds are measured in oatmeal and infant cereal using ion-exchange polymer-based particles for HPLC and SPE. Low level detection was obtained.
Rapid Analysis of Caffeinated Energy Drinks by HPLC on Ascentis Express
The sample complexity makes it important to use highly-efficient, highly-selective phases and columns that are compatible with different detection systems to maximize the information from HPLC experiments. Ascentis Express Fused-Core® columns meet these requirements.
Ascentis ® Express HILIC U/HPLC Columns
For separation of polar compounds including polar neutrals, polar acids, and polar and non-polar basic amines use our Ascentis® Express HILIC column.
Determination of Chlorogenic acid and Baicalin in Compounded Lonucerae Japonicae Flos using a Discovery® HS C18 Column
Extraction and analyses of chlorogenic acid and baicalin active ingredients in traditional Chinese medicine (TCM) according to Chinese pharmacopeia monograph by HPLC with Discovery® C18 column to check: chromatographic data, linearity, specificity and repeatability, LOQ and LOD
HPLC Analysis of Sugars on Ascentis® Si
Separation of Sucrose; Maltose; Maltotriose
Ion Chromatography & Cation Suppression Straightforward Cation Analysis at Trace Levels
Ammonium determination in acidic solutions with Metrosep C Supp 2 column using the acidic binary IC eluent nitric acid/rubidium nitrate concentrate and the sodium bicarbonate/sodium carbonate suppressor regenerant.
HPLC Tips & Tricks: Mobile Phase Preparation Part 2 - Buffers
Learn the tips and tricks of selecting and preparing a suitable mobile phase buffer for your HPLC separations and method developments for samples that contain ionizable compounds.
HPLC analysis of Letrozole and its impurities by following the USP Guidelines Using a Purospher® STAR RP18e Column and UV Detection
An application note concerning the HPLC analysis of letrozole and its impurities by following the USP43-NF38 Guidelines using a Purospher® STAR RP18e Column.
LC/MS Analysis of Ethanol Metabolites in Urine on Ascentis® Express OH5 after Dilution with Deuterated Internal Standards
The method shown uses HILIC mode on an Ascentis® Express OH5 column to retain both analytes well, making it very likely to be more robust and reliable, as well as highly MS-friendly.
HPLC Analysis of Xanthines on Purospher® STAR RP-18 endcapped
Xanthine is a purine base found in most human body tissues and fluids as well as in other organisms. Methylated xanthines (methylxanthines), which include caffeine, paraxanthine, theobromine, and theophylline, commonly used for their effects as mild stiµlants and as bronchodilators
LC/MS Analysis of Illicit Bath Salts on Ascentis® Express HILIC, Fast Analysis
Separation of Butylone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Ethylone hydrochloride, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Mephedrone hydrochloride solution, 1.0 mg/mL
Ascentis® Express UHPLC Columns with 2.0 μm Fused-Core Particles
Ascentis® Express columns with 2.0 μm particles show comparable efficiency at a significantly lower pressure than competitor columns that use smaller particles.
Separation of Organic Acids with 100% aqueous mobile phase using an Ascentis® Express AQ-C18 HPLC Column
A new RP-HPLC method is proposed for the determination of organic acids in 100% aqueous mobile phase using an Ascentis® Express AQ-C18 column
Dyestuff Analyses on Historic Objects by LC-ESI-MS/MS Using a Superspher RP-18 HPLC Column
In this study, LC-ESI-MS/MS under reversed phase conditions using a Superspher RP-18 column is applied to analyze dyestuffs of a reddish historic textile from South America.
Supelco Preparative HPLC products for Pharmaceutical Development and Production
Supelco Preparative HPLC products for Pharmaceutical Development and Production
How to Select the Right Water Purification System for Your Lab
Technical article on Selecting the Right Water Purification System
HPLC Analysis of Proteins on BIOshell™ A400 Protein C4, Rapid Separation at Elevated Temperature
For use as a marker in SDS-PAGE; lactate dehydrogenase; contaminant; L-Lactic Dehydrogenase from rabbit muscle, Type XI, lyophilized powder, 600-1,200 units/mg protein
Determination of Buprenorphine and Norbuprenorphine in Urine Using LC-MS/MS
Determination of Buprenorphine and Norbuprenorphine in Urine Using LC-MS/MS
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