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Palabra clave:'L7381'
Mostrando 1-30 of 101 resultados para "L7381" en el plazo de Papeles
NeuroD1 regulates expression of thyroid hormone receptor beta2 and cone opsins in the developing mouse retina
Liu H, et al.
The Journal of Neuroscience, 28(3), 749-756 (2008)
Binding sugars: from natural lectins to synthetic receptors and engineered neolectins
Arnaud J, et al.
Chemical Society Reviews, 42(11), 4798-4813 (2013)
Hang Yu et al.
Biomaterials, 219, 119368-119368 (2019-07-28)
Acute kidney injury (AKI) is associated with high mortality and morbidity with no effective treatment available at present, which greatly escalates the risk of chronic kidney disease. Nanotechnology-based drug delivery for targeting renal tubules offers a new strategy for AKI
Venkateshappa Arjun et al.
Andrologia, 54(7), e14431-e14431 (2022-04-23)
Sperm mitochondrion is one of the major susceptible organelles that get damaged during cryopreservation. The study aimed to minimize mitochondrial dysfunction and oxidative stress during sperm cryopreservation using mitochondria-specific antioxidants. For this, semen was collected from five buffalo bulls (3
Nobuhiro Tanno et al.
iScience, 25(4), 104008-104008 (2022-03-22)
Meiotic prophase I is a prolonged G2 phase that ensures the completion of numerous meiosis-specific chromosome events. During meiotic prophase I, homologous chromosomes undergo synapsis to facilitate meiotic recombination yielding crossovers. It remains largely elusive how homolog synapsis is temporally
Zubing Cao et al.
Animal reproduction, 15(1), 29-38 (2018-08-16)
Air phase is an indispensable environmental factor affecting oocyte maturation and early embryo development. Human exhaled air was previously proved to be a reliable and inexpensive atmosphere that sustains normal early development of mouse and bovine embryos. However, whether human
Patrizia Colucci et al.
Pharmaceutics, 15(4) (2023-04-28)
Neuroprotective drug delivery to the posterior segment of the eye represents a major challenge to counteract vision loss. This work focuses on the development of a polymer-based nanocarrier, specifically designed for targeting the posterior eye. Polyacrylamide nanoparticles (ANPs) were synthesised
Caner Öztürk et al.
Acta veterinaria Hungarica, 65(3), 429-439 (2017-09-29)
The present study was conducted to examine the protective role of arginine and trehalose on post-thaw bull sperm and oxidative stress parameters. Five ejaculates for each bull were used in the study. Each ejaculate, split into three equal aliquots and
Yuki Osawa et al.
eLife, 10 (2021-05-12)
The male germ cells must adopt the correct morphology at each differentiation stage for proper spermatogenesis. The spermatogonia regulates its differentiation state by its own migration. The male germ cells differentiate and mature with the formation of syncytia, failure of
Liga Wuri et al.
Molecular reproduction and development, 86(7), 825-834 (2019-05-16)
Generation of high quality mouse metaphase II oocytes is an integral part for efficient in vitro fertilization (IVF), and subsequent embryo production for reproductive studies and genome banking. The main objectives of this study were to investigate the impact of
L Martínez-Fresneda et al.
Domestic animal endocrinology, 72, 106372-106372 (2019-08-23)
In small ruminants, testosterone and prolactin plasma concentrations show circannual fluctuations as an adaptation mechanism to their seasonal breeding behavior. Sperm resistance to the freezing-thawing process shows seasonal fluctuation throughout the year, with lower sperm freezability at the beginning of
Alessandra Calvi et al.
Developmental biology, 407(2), 321-330 (2015-09-30)
One of the more dramatic examples of cellular reorganization occurs during spermiogenesis in which a roughly spherical spermatid is transformed into a mature sperm cell. A highlight of this process involves nuclear remodeling whereby the round spermatid nucleus is sculpted
Feifei Kong et al.
Cell death & disease, 8(10), e3121-e3121 (2017-10-13)
Liver serine/threonine kinase B1 (LKB1) is a tumor suppressor associated with the pathogenesis of Peutz-Jeghers syndrome. Affected males are at increased risk of developing Sertoli cell tumors and display defective spermatogenesis. Male mice lacking the short isoform (Lkb1S) of Lkb1
Md Abul Hasnat et al.
Immunology and cell biology, 100(8), 605-623 (2022-06-03)
Studies have highlighted a critical role for autophagy in the regulation of multiple cytokines. Autophagy inhibits the release of interleukin (IL)-1 family cytokines, including IL-1α, IL-1β and IL-18, by myeloid cells. This, in turn, impacts the release of other cytokines
Mustafa Numan Bucak et al.
Andrology, 10(3), 585-594 (2021-11-16)
Sperm cryopreservation has been widely used in the field of reproductive biotechnology. It applies to certain males of economic and scientific values, including livestock breeds or endangered animal species. The development of a semen extender with a low cryoprotectant concentration
Minhua Yao et al.
PloS one, 18(4), e0285016-e0285016 (2023-04-28)
Guinea pigs are a valuable animal model for studying various diseases, including reproductive diseases. However, techniques for generating embryos via embryo engineering in guinea pigs are limited; for instance, in vitro maturation (IVM) technique is preliminary for guinea pig oocytes.
Xiaoming Zhang et al.
iScience, 25(4), 104058-104058 (2022-04-02)
Histone methylation, particularly at the H3K4 position, is thought to contribute to the specification of photoreceptor cell fate; however, the mechanisms linking histone methylation with transcription factor transactivation and photoreceptor gene expression have not yet been determined. Here, we demonstrate
Fatemeh Tanhaye Kalate Sabz et al.
Andrologia, 54(7), 1618-1630 (2022-05-12)
Poor sperm quality in oligoasthenoteratospermia patients negatively affects assisted reproductive technology outcomes. Therefore, the development of sperm media is necessary to improve sperm parameters. This study investigated the effect of GM-CSF via PI3K/AKT pathway on sperm quality in OAT patients.
Xiaoyan Liu et al.
Environmental and molecular mutagenesis, 59(3), 223-233 (2017-12-30)
Sodium fluoride (NaF) is used as a medicine to prevent tooth decay; however, excessive NaF could cause a pathological damage to the health. Recent studies showed that NaF impaired mouse oocyte maturation, included of abnormal spindle configuration, actin cap formation
Hossam H Shawki et al.
PloS one, 14(4), e0214687-e0214687 (2019-04-02)
Calcium-binding proteins regulate ion metabolism and the necessary signaling pathways for the maturational events of sperm. Our aim is to identify the novel calcium-binding proteins in testis. The gene EFCAB2 (GenBank NM_026626.3, NP_080902.1) was not previously examined, and its properties
Liga Wuri et al.
Reproduction, fertility, and development, 32(5), 474-483 (2020-01-24)
This study compared the morphometric, subcellular characteristics, in vitro fertilisation (IVF) and embryonic developmental potential of metaphase II (MII) mouse oocytes obtained from females superovulated with either anti-inhibin serum-human chorionic gonadotrophin (AIS-hCG) or pregnant mare serum gonadotrophin (PMSG)-hCG. The oocyte's
Jamie L Stewart et al.
Animal reproduction science (2018-05-24)
White-tailed deer farming is a growing industry in the United States, with breeding operations contributing significantly to the industry's economic impact. Artificial insemination with frozen semen allows for selection and dissemination of valuable genetics, yet surprisingly little is known regarding
Mario Crespo-Moral et al.
PloS one, 15(1), e0227732-e0227732 (2020-01-14)
The ocular surface of the white domestic pig (Sus scrofa domestica) is used as a helpful model of the human ocular surface; however, a complete histological description has yet to be published. In this work, we studied porcine eyeballs with
D A Galarza et al.
Animal reproduction science, 192, 261-270 (2018-03-28)
Density-gradients centrifugation (DGC) and filtration columns (FC) are used to separate deformed or dead sperm, debris, and other cells that may negatively affect the fertilizing capacity of sperm in fresh, chilled and frozen/thawed semen. The present study was conducted to
Tapasi Rana et al.
Biochimica et biophysica acta. Molecular basis of disease, 1863(1), 92-102 (2016-10-18)
Expression of T17M rhodopsin (T17M) in rods activates the Unfolded Protein Response (UPR) and leads to the development of autosomal dominant retinitis pigmentosa (adRP). The rod death occurs in adRP retinas prior to cone photoreceptor death, so the mechanism by
Luis Águila et al.
Molecular reproduction and development, 84(7), 649-659 (2017-05-18)
The efficiency of intracytoplasmic sperm injection (ICSI) in bovines is low compared to other species due in part to inadequate egg activation and sperm nucleus decondensation after injection. We hypothesized that this low efficiency is due to the lack of
Napapach Chauychu-Noo et al.
Cryobiology, 98, 57-62 (2021-01-06)
Oxidative stress due to cryopreservation has been considered as a major factor in sperm damage. Supplementation of the diet with different concentrations of organic selenium has been proposed to improve the quality of fresh and frozen-thawed semen in different breeds
Napapach Chuaychu-Noo et al.
Cryobiology, 74, 8-12 (2017-01-04)
Little is known about the effects of Cholesterol-Loaded Cyclodextrin (CLC) on post-thaw semen quality in chicken. The aim of the present study is to investigate the efficacy of CLC levels (0, 1, 2 and 3 mg/mL Schramm diluent) on post-thawed semen
Jing Wang et al.
Investigative ophthalmology & visual science, 60(13), 4397-4407 (2019-10-23)
Retinitis pigmentosa (RP), a retinal photoreceptor degeneration, typically affects rod function and subsequently cones. Activation of sigma 1 receptor (Sig1R) has been shown to preserve cone function through 6 weeks in the rd10 mouse model of RP, when mice were
The m6A reader PRRC2A is essential for meiosis I completion during spermatogenesis.
Tan, et al.
Nature Communications, 14, 1636-1636 (2023)
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