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Tangzhao Liang et al.
FEBS open bio, 7(11), 1722-1736 (2017-11-11)
The beneficial effects of combined use of mesenchymal stem cells (MSCs) and endothelial progenitor cells (EPCs) on tissue repair and regeneration after injury have been demonstrated, but the underlying mechanism remains incompletely understood. This study aimed to investigate the effects
M V Dolgushin et al.
Morfologiia (Saint Petersburg, Russia), 142(4), 62-66 (2012-12-15)
The functional-metabolic response peculiarities of the rat blood cells to isoniazid (one of the main antituberculosis medications) were studied. Isoniazid or its complex with pyridoxine were administrated orally for 3 months in therapeutic (5 mg/kg) and the toxic (100 mg/kg)
Fei Xu et al.
Photodiagnosis and photodynamic therapy, 30, 101713-101713 (2020-03-14)
A photosensitizer is a light-activated molecule that can generate reactive oxygen species or directly interact with nucleic acids. Both consequences can be applied to reduction of pathogens in various media and to selectively attack tumor cells. Numerous natural and synthesized
Berberine compounds improves hyperglycemia via microbiome mediated colonic TGR5-GLP pathway in db/db mice.
Li, et al.
Biomedicine and Pharmacotherapy, 132, 110953-110953 (2021)
Mehran Dastmalchi et al.
Plant physiology, 181(3), 916-933 (2019-08-31)
Although opiate biosynthesis has been largely elucidated, and cell-to-cell transport has been long postulated, benzylisoquinoline alkaloid (BIA) transporters from opium poppy (Papaver somniferum) have not been reported. Investigation of a purine permease-type sequence within a recently discovered opiate biosynthetic gene
N Kodambashi Emami et al.
British poultry science, 58(1), 87-94 (2017-01-06)
1. The aim of this experiment was to study the interactive effect of rearing temperature and dietary supplementation of arginine (Arg) or guanidinoacetic acid (GAA) on performance, gut morphology and ascites indices in broiler chickens raised under the same condition
Md Tawheed Hasan et al.
Journal of microbiology and biotechnology, 28(9), 1433-1442 (2018-09-05)
To identify and quantify the effects of a combination of dietary 1 × 108 CFU/g Lactococcus lactis subsp. lactis I2 (LI2) and 0.1% β-glucooligosaccharides (BGO) on the growth and immunity of olive flounder (Paralichthys olivaceus), a feeding experiment was conducted.
Cristian Del Bo' et al.
Clinical nutrition (Edinburgh, Scotland), 38(2), 575-583 (2018-03-04)
Vegetarians and vegans are more vulnerable to vitamin B12 deficiency with severe risks of megaloblastic anemia, cognitive decline, neuropathy, and depression. An easy and simple method of supplementation consists of taking one weekly dosage of 2000 μg. However, single large oral
Qingquan Ma et al.
Food & function, 12(1), 267-277 (2020-12-11)
Emerging evidence shows that amino acids can modulate lipid metabolism. Aromatic amino acids (AAAs) serve as important precursors of several neurotransmitters and metabolic regulators that play a vital role in regulating nutrient metabolism. But whether AAAs have a lipid-lowering function
Tingting Wang et al.
Ecotoxicology and environmental safety, 185, 109686-109686 (2019-09-24)
Gestational exposure to PM2.5 is a worldwide environmental issue associated with long-lasting behavior abnormalities and neurodevelopmental impairments in the hippocampus of offspring. PM2.5 may induce hippocampus injury and lead to autism-like behavior such as social communication deficits and stereotyped repetitive
Vinay Kumar et al.
International journal of biological macromolecules, 119, 320-334 (2018-07-22)
Pyridoxal kinase (PdxK, EC is an important enzyme of vitamin B6 salvage pathway which is required for phosphorylation of B6 vitamers. In the present study, pyridoxal kinase (pdxK) gene from Leishmania donovani (LdPdxK) was cloned and a 33 kDa protein
Chen Li et al.
Cellular and molecular biology (Noisy-le-Grand, France), 64(10), 119-124 (2018-08-08)
Pyridoxine is a water- soluble pyridine derivative. The effect of pyridoxine in cell models of Alzheimer's disease (AD), and the potential mechanisms involved, are not fully understood. In this study, the anti-AD effects of pyridoxine were studied in an AD
G Ravi et al.
Journal of immunological methods, 445, 59-66 (2017-03-23)
Riboflavin (vitamin B
Agnieszka Wasilewska et al.
Medical science monitor : international medical journal of experimental and clinical research, 9(3), CR147-CR151 (2003-03-18)
There is increasing evidence that plasma homocysteine level is an independent risk factor for atherosclerosis. Low levels of serum folates, cobalamin and pyridoxine are associated with increased risk of cardiovascular disease. Most dietary products contain cholesterol as well as methionine
Iga Rybicka et al.
Journal of nutritional science and vitaminology, 63(2), 125-132 (2017-05-30)
Gluten-free (GF) products are those with a natural absence or acceptable level (<20 mg/kg) of gluten. They should be a part of a diet for people with gluten-related disorders, like celiac disease. Recently the popularity of a gluten-free diet (GFD)
Cristina María López et al.
Plants (Basel, Switzerland), 9(4) (2020-04-08)
Drought is one of the most critical factors limiting legume crop productivity. Understanding the molecular mechanisms of drought tolerance in the common bean is required to improve the yields of this important crop under adverse conditions. In this work, RNA-seq
Frida Niss et al.
Environmental science and pollution research international, 25(12), 12183-12188 (2018-03-12)
The use of in vitro bioassays for studies of toxic activity in environmental water samples is a rapidly expanding field of research. Cell-based bioassays can assess the total toxicity exerted by a water sample, regardless whether the toxicity is caused
Xushen Han et al.
Journal of agricultural and food chemistry, 67(25), 7082-7086 (2019-06-15)
Vitamins are important nutrients for many fermentations, but they are generally costly. Agricultural lignocellulose biomass contains considerable amounts of vitamin B compounds, but these water-soluble vitamins are easily lost into wastewater discharge during pretreatment or detoxification of lignocellulose in biorefinery
Sabrina Bochicchio et al.
International journal of pharmaceutics, 525(2), 377-387 (2017-02-13)
Tailored developed nanoliposomes loaded with a siRNA against the transcription factor E2F1 (siE2F1), were produced and delivered to human colorectal adenocarcinoma cell lines and to intestinal human biopsies. siE2F1 loaded nanoliposomes were produced through a dedicated ultrasound assisted technique producing
Florian Finkernagel et al.
Theranostics, 9(22), 6601-6617 (2019-10-08)
The peritoneal fluid (ascites), replete with abundant tumor-promoting factors and extracellular vesicles (EVs) reflecting the tumor secretome, plays an essential role in ovarian high-grade serous carcinoma (HGSC) metastasis and immune suppression. A comprehensive picture of mediators impacting HGSC progression is
Daojin Li et al.
Analytical biochemistry, 561-562, 18-26 (2018-09-21)
Vitamin B12 (VB12) has an important function in human physiology. However, analysis of VB12 at natural levels in foods or biological samples is difficult because of its very low concentration level and the presence of high-abundance components which can interfere
Seungho Ryu et al.
European journal of clinical nutrition, 73(10), 1343-1351 (2018-12-14)
The objective of this study was to evaluate secular trends in Dietary Inflammatory Index (DII) scores in the United States between 1999 and 2014. Data from adults over 19 years from the 1999 to 2014 National Health and Nutrition Examination
Jyotirmaya Behera et al.
Biochemical and biophysical research communications, 510(1), 135-141 (2019-01-27)
Bone marrow (BM)-derived endothelial progenitor cells (EPCs) are the key players in angiogenesis and vascular function. Cystathionine-β-synthase (CBS), an H2S-generating enzyme in methionine metabolism, regulates the function of these EPCs. This study aims to examine whether CBS hyper-methylation contributes to
Wei Zeng et al.
Biomedical chromatography : BMC, 34(4), e4795-e4795 (2020-01-23)
In this study, we focused on studying the changes in urine metabolites in hyperlipidemic rats using ultra-performance liquid chromatography coupled with quadrupole time-of-fight mass spectrometry (UPLC-Q-TOF/MS) and metabolomics, as well as the effect of Citri Reticulatae Chachiensis Pericarpium (CRCP) on
Young-Mi Go et al.
PloS one, 10(11), e0142916-e0142916 (2015-11-19)
High-resolution metabolomics has created opportunity to integrate nutrition and metabolism into genetic studies to improve understanding of the diverse radiation of primate species. At present, however, there is very little information to help guide experimental design for study of wild
Chenguang Wang et al.
Immunity, 48(4), 675-687 (2018-04-15)
Manganese (Mn) is essential for many physiological processes, but its functions in innate immunity remain undefined. Here, we found that Mn2+ was required for the host defense against DNA viruses by increasing the sensitivity of the DNA sensor cGAS and
Reactivation of latent tuberculosis in a Crohn's patient after TB prophylaxis treated with adalimumab.
Freddy Caldera et al.
The American journal of gastroenterology, 108(7), 1181-1182 (2013-07-04)
Vijay P Singh et al.
The Journal of organic chemistry, 78(4), 1478-1487 (2013-01-16)
Vitamin B6 is involved in a variety of enzymatic transformations. Some recent findings also indicate an antioxidant role of the vitamin in biological systems. We set out to turn pyridoxine (1a) into a catalytic chain-breaking and hydroperoxide-decomposing antioxidant by replacing
Mohamed K Abd El-Rahman et al.
Talanta, 221, 121409-121409 (2020-10-21)
Choline (Ch+), is a vitamin-like essential water-soluble organic micronutrient. The US-FDA requires that infant formula not made from cow's milk must be supplemented with Ch+. Direct determination of Ch+ in milk powders and infant formulas is a challenging task due
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