Showing 1-19 of 19 resultados for "SRP3138"
Dovitinib preferentially targets endothelial cells rather than cancer cells for the inhibition of hepatocellular carcinoma growth and metastasis.
Chen ZY, et al.
Journal of Translational Medicine, 10, 245-245 (2012)
Mechanism of platelet-derived growth factor (PDGF) AA, AB, and BB binding to alpha and beta PDGF receptor.
Fretto LJ, et al.
The Journal of Biological Chemistry, 268, 3625-3631 (1993)
The biology of platelet-derived growth factor.
R Ross et al.
Cell, 46(2), 155-169 (1986-07-18)
Structural and functional studies on platelet-derived growth factor.
C H Heldin
The EMBO journal, 11(12), 4251-4259 (1992-12-01)
Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification.
Vanlandewijck M, et al.
PLoS ONE, 10, e0143407-e0143407 (2015)
Human placenta-derived multipotent mesenchymal stromal cells involved in placental angiogenesis via the PDGF-BB and STAT3 pathways.
Chen CY, et al.
Biology of Reproduction, 93, 103-103 (2015)
Luise Landreh et al.
The Journal of clinical endocrinology and metabolism, 99(7), E1227-E1235 (2014-04-02)
We aim to examine the steroidogenic phenotype and the differentiation potential of human testicular peritubular cells (HTPCs) and to explore their possible relationship to the adult Leydig cell lineage. The cells of the adult Leydig cell lineage may reside in...
Decorin inhibition of PDGF-stimulated vascular smooth muscle cell function: potential mechanism for inhibition of intimal hyperplasia after balloon angioplasty.
Nili N, et al.
The American Journal of Pathology, 163, 869-878 (2003)
Roles of PDGF in animal development.
Hoch RV and Soriano P
Development, 130, 4769-4784 (2003)
Human testicular peritubular cells host putative stem Leydig cells with steroidogenic capacity.
Landreh L, et al.
The Journal of Clinical Endocrinology and Metabolism, 99, E1227-E1235 (2014)
Platelets in inflammation and atherogenesis.
Gawaz M, et al.
The Journal of Clinical Investigation, 115, 3378-3384 (2005)
Chin-Chang Cheng et al.
International journal of molecular sciences, 20(6) (2019-03-27)
Pulmonary arterial hypertension (PAH) is characterized by pulmonary arterial proliferation and remodeling, resulting in a specific increase in right ventricle systolic pressure (RVSP) and, ultimately right ventricular failure. Recent studies have demonstrated that caffeic acid phenethyl ester (CAPE) exerts a...
A role for the polysialic acid-neural cell adhesion molecule in PDGF-induced chemotaxis of oligodendrocyte precursor cells.
Zhang H, et al.
Journal of Cell Science, 117, 93-103 (2004)
Arterial smooth muscle cells express platelet-derived growth factor (PDGF) A chain mRNA, secrete a PDGF-like mitogen, and bind exogenous PDGF in a phenotype- and growth state-dependent manner.
Sjolund M, et al.
The Journal of Cell Biology, 106, 403-413 (1998)
Pu Yang et al.
Surgery, 159(2), 602-612 (2015-09-22)
With the diverse origin of neointimal cells, previous studies have documented differences of neointimal cell lineage composition across models, but the animal-to-animal difference has not attracted much attention, although the cellular heterogeneity may impact neointimal growth and its response to...
Zhi-Yuan Chen et al.
Journal of translational medicine, 10, 245-245 (2012-12-12)
Dovitinib is a receptor tyrosine kinase (RTK) inhibitor targeting vascular endothelial growth factor receptors, fibroblast growth factor receptors and platelet-derived growth factor receptor β. Dovitinib is currently in clinical trials for the treatment of hepatocellular carcinoma (HCC). In this study...
Thomas Daubon et al.
Nature communications, 10(1), 1146-1146 (2019-03-10)
We undertook a systematic study focused on the matricellular protein Thrombospondin-1 (THBS1) to uncover molecular mechanisms underlying the role of THBS1 in glioblastoma (GBM) development. THBS1 was found to be increased with glioma grades. Mechanistically, we show that the TGFβ...
T Collins et al.
Nature, 328(6131), 621-624 (1987-08-13)
Platelet-derived growth factor (PDGF) is a basic protein of relative molecular mass 30,000 (Mr 30K) composed of two polypeptide chains, designated PDGF A and PDGF B. The B-chain is encoded by the c-sis gene, the cellular counterpart of the simian...
Low-level genomic instability is a feature of papillary thyroid carcinoma: an array comparative genomic hybridization study of laser capture microdissected papillary thyroid carcinoma tumors and clonal cell lines.
Finn S, et al.
Archives of Pathology & Laboratory Medicine, 131, 65-73 (2007)

Redes sociales

LinkedIn icon
Twitter icon
Facebook Icon
Instagram Icon


Investigación. Desarrollo. Producción.

Somos un proveedor líder para la industria de Ciencias de la Vida con soluciones y servicios para investigación, desarrollo y producción biotecnológicos, y para desarrollo y producción de tratamientos farmacéuticos

© 2021 Merck KGaA, Darmstadt, Alemania y/o sus filiales. Todos los derechos reservados.

Queda estrictamente prohibida la reproducción sin permiso de cualquiera de los materiales de la página web.