Palmitoylation and the trafficking of peripheral membrane proteins.

Biochemical Society transactions (2013-01-30)
Luke H Chamberlain, Kimon Lemonidis, Maria Sanchez-Perez, Martin W Werno, Oforiwa A Gorleku, Jennifer Greaves
RESUMEN

Palmitoylation, the attachment of palmitate and other fatty acids on to cysteine residues, is a common post-translational modification of both integral and peripheral membrane proteins. Dynamic palmitoylation controls the intracellular distribution of peripheral membrane proteins by regulating membrane-cytosol exchange and/or by modifying the flux of the proteins through vesicular transport systems.

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