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Merck

IL6

interleukin 6 (interferon, beta 2)

Synonyms:
BSF2, HGF, HSF, IFNB2, IL-6
Species:
UniProtKB ID:
Gene ID:
  • Human(3569) Summary: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
  • Mouse(16193) interleukin 6
  • Rat(24498) interleukin 6
  • Zebrafish(100885851) interleukin 6 (interferon, beta 2)
  • chicken(395337) interleukin 6 (interferon, beta 2)
  • dog(403985) interleukin 6 (interferon, beta 2)
  • domestic cat(493687) interleukin 6 (interferon, beta 2)
  • Horse(100034196) interleukin 6 (interferon, beta 2)
  • cow(517016) interleukin 6 (interferon, beta 2)
  • cow(280826) interleukin 6 (interferon, beta 2)
  • Goat(100860785) interleukin 6 (interferon, beta 2)
  • sheep(443406) interleukin 6 (interferon, beta 2)
  • Domestic Rabbit(100008733) interleukin 6 (interferon, beta 2)
  • naked mole-rat(101702602) interleukin 6 (interferon, beta 2)

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Rhesus Macaque IL6 / Interleukin-6 ELISA Kit, ,
Species
Rat IL-6 ELISA Kit, for serum, plasma and cell culture supernatants,
Species
rat
Rat Interleukin-6 ELISA Kit, for for cell lysate and tissue lysate,
Species
rat
Mouse IL-6 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
Mouse IL-6 ELISA Kit, for cell and tissue lysates,
Species
rat

Small Molecule - Antagonist

Product Number
Description
Species
Probucol, analytical standard,
Species
human
4-Hydroxytamoxifen, analytical standard, (E) and (Z) isomers (50:50),
Species
human, rat

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-IL6 antibody produced in mouse, clone 2D12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-IL-6 Antibody, clone 1G18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
affinity binding assay
flow cytometry

immunohistochemistry

western blot
Anti-IL-6 / IFNb2 Reference Antibody, ,
Species Reactivity
human
Application
ELISA
Anti-IL6 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
flow cytometry
immunohistochemistry

western blot
Anti-IL6 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry

western blot

Proteins

Product Number
Description
Species
Interleukin-6, human (hIL-6), recombinant (E. coli),
Species
human
IL-6 from mouse, Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
Species
mouse
Interleukin-6 from rat, IL-6, recombinant, expressed in E. coli, buffered aqueous solution, suitable for cell culture,
Species
rat

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human IL6,
Species
human
MISSION® esiRNA, targeting mouse Il6,
Species
mouse