RB1
retinoblastoma 1
Synonyms:
OSRC, RB, p105-Rb, pRb, pp110
Species:
Human RB1 (5925), Mouse Rb1 (19645), Rat Rb1 (24708), chicken RB1 (386582), Zebrafish rb1 (777733), domestic cat RB1 (101101356), dog RB1 (476915), cow RB1 (534712), Horse RB1 (100057080), sheep RB1 (100144755) ...More
UniProtKB ID:
Gene ID:
- Human(5925) Summary: The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
- Mouse(19645) retinoblastoma 1
- Rat(24708) retinoblastoma 1
- chicken(386582) retinoblastoma 1
- Zebrafish(777733) retinoblastoma 1
- domestic cat(101101356) retinoblastoma 1
- dog(476915) retinoblastoma 1
- cow(534712) retinoblastoma 1
- Horse(100057080) retinoblastoma 1
- sheep(100144755) retinoblastoma 1
- Domestic Rabbit(100357431) retinoblastoma 1
- domestic guinea pig(100716297) retinoblastoma 1
- naked mole-rat(101703701) retinoblastoma 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RB antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti- RB antibody produced in rabbit, ,
Species Reactivity
Application
immunohistochemistry
western blot
western blot
Anti-Phospho-RB-S780 antibody produced in rabbit, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti RB1 Antibody, clone 23GB2535, Rabbit Monoclonal, clone 23GB2535, recombinant rabbit monoclonal, expressed in HEK293 cells,
Species Reactivity
human
Application
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Rb Antibody, clone 2M15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot