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202398

Sigma-Aldrich

Poly(ethylene glycol)

greener alternative

average Mn 400

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Synonym(s):
PEG
Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.23

form

viscous liquid

Quality Level

mol wt

Mn 380-420
average Mn 400

greener alternative product characteristics

Safer Solvents and Auxiliaries
Learn more about the Principles of Green Chemistry.

refractive index

n20/D 1.466

pH

4.5-7.5

viscosity

7.3 cSt(210 °F)(lit.)

mp

4-8 °C (lit.)

density

1.128 g/mL

Ω-end

hydroxyl

α-end

hydroxyl

greener alternative category

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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2023718126081300
Poly(ethylene glycol) average Mn 400

202398

Poly(ethylene glycol)

Poly(ethylene glycol) average Mn 300

202371

Poly(ethylene glycol)

Poly(ethylene glycol) average Mn 6,000

81260

Poly(ethylene glycol)

Poly(ethylene glycol) average Mn 20,000

81300

Poly(ethylene glycol)

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

200

Ω-end

hydroxyl

Ω-end

hydroxyl

Ω-end

hydroxyl

Ω-end

hydroxyl

α-end

hydroxyl

α-end

hydroxyl

α-end

hydroxyl

α-end

hydroxyl

mol wt

Mn 380-420, average Mn 400

mol wt

Mn 285-315, average Mn 300

mol wt

Mn 5,000-7,000, average Mn 6,000

mol wt

average Mn 20,000

density

1.128 g/mL

density

1.125 g/mL at 25 °C

density

-

density

-

General description

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are non-toxic, FDA-approved, generally non-immunogenic, and frequently used in many biomedical applications including bioconjugation, drug delivery, surface functionalization, and tissue engineering. In drug delivery, PEGs can be used as linkers for antibody-drug conjugates (ADCs) or as a surface coating on nanoparticles to improve systemic drug delivery.

Application

Poly(ethylene glycol) (PEG) has been used as a coating agent for the synthesis and in vitro safety assessment of magnetic bacterial cellulose (MBC) pellicles, performed on porcine aortic smooth muscle cells (PAOSMC). PEG provides a compatible surface for cell culture, since uncoated iron oxide NPs are considered cytotoxic to cells. It has also been used as a plasticizer in investigating the effectiveness of polyvinylpyrrolidone microneedles for transdermal delivery of functional collagen using porcine skin, adult human skin analog and human foreskin. Microneedles obtained, were reportedly characterized by various analytical and bio-analytical techniques.
Used in conjunction with carbon black to form a conductive composite. Polymer nanospheres of poly(ethylene glycol) were used for drug delivery.

Legal Information

Selectfluor is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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25G
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Immune therapies have had limited efficacy in high-grade serous ovarian cancer (HGSC), as the cellular targets and mechanism(s) of action of these agents in HGSC are unknown. Here we performed immune functional and single-cell RNA sequencing transcriptional profiling on novel
Akashi, M., Akagi, T.
Yuki Gosei Kaguku Kyokaishi, 65, 520-520 (2004)
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Physical review. E, 96(6-1), 062803-062803 (2018-01-20)
The evaporation of droplets can give rise to a wide range of interesting phenomena in which the dynamics of the evaporation are crucial. In this work, we find simple scaling laws for the evaporation dynamics of axisymmetric droplets pinned on
Synthesis and in vitro safety assessment of magnetic bacterial cellulose with porcine aortic smooth muscle cells
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Journal of Biomedical Materials Research Part A, 104(11), 2801-2809 (2016)
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Related Content

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

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